Hi everyone, I just went to the doctor today and got some interesting results. I got a methylation panel done through NurtiPath in Melbourne and thought other Australians might like to hear about my experience. I was also hoping to get some advice regarding how to interpret and what to do (supplements etc.) in response to these results I had quite a few tests done, the MTHFR gene test with Healthscope, which found that I was heterozygous for C677t, it was just a cheek swab - i believe it cost $50. I had a plasma amino acid profile done which was generally normal, but found I had high glycine which my doctor tells me can also be a result of poor methylation. Strangely, my plasma homocysteine levels were normal. The glycine result was 422 (normal upper limit was 400). The most interesting test was the methylation panel with NutriPath. I know this panel isn't as thorough as some that can be done internationally, but I thought it might give some useful info - it cost around $450. Getting it done was simple I just went to QML (I'm in Brisbane) and they took the blood, prepared it and sent it to the NutriPath lab according to their instructions. The results showed that I have high s-adenosyl homocysteine (SAH) and a slightly low SAMe to SAH ratio. It also showed that 5-mthf levels were a little on the lowish side - i've pasted results below. So, for any Australians interested in getting a methylation panel done locally, NutriPath seem pretty good but pricey. This test only covered SAMe, SAH, and different folates, though they do offer other tests which cover different methylation related stuff. I'd really love to know what others have taken to reduce SAH, my doctor said I should take SAMe, but I don't know about that, not many people seem to recommend it. It seems to be that TMG and 5-mthf are recommended. Any help or advice on what these results mean (SAH and glycine especially) and what to do regarding these results would be very much appreciated! Thanks!