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Help! Food sensitivites getting WORSE with methylation protocol

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by chilove, Mar 26, 2012.

  1. chilove

    chilove Senior Member

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    Hi all,

    I've been on Fredd's protocol for about 2 months now and my food sensitivities are getting worse not better... I'm now reacting to foods that were "safe" for many years and that I ate just a few weeks ago with no problems.

    Has anyone else experienced this or can someone help me figure out why?

    Thanks so much!

    Audrey
     
  2. Sparrow

    Sparrow Senior Member

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    Maybe your immune system in general is ramping up? Or freaking out a little because there are other toxins floating around now as your body systems start moving again and dealing with the backlog? It could be that part of your immune system was always way stronger than the other, but because both were so low you didn't really notice as much, I guess. Not sure.

    Are you certain that the problem is allergy related, and not some other feature of certain foods, or something that happens at a particular time of day? I've had problems with foods before that turned out to instead be a non-allergy issue with something in them (sulfur, etc).

    Quercetin can supposedly help to calm down allergies. ...Though you would probably still need time for those you have to fade enough for you to eat those foods again. Immune modulators might be something to try too, though you may not want to go with something too hardcore while you're also implementing the methylation stuff and not yet stable with it. Maybe something like astragalus? That's all I can think of right now.

    Food allergies stink. Hope they calm down for you soon!
     
  3. richvank

    richvank Senior Member

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    Hi, Audrey.

    Food sensitivities (if they are the IgG type) result from intestinal permeability ("leaky gut syndrome"). Protein fragments from food that have not been completely digested are able to pass from the gut into the blood, and the immune system sees them as foreign proteins and makes IgG antibodies against them. I don't think it's likely that Freddd's protocol would cause more intestinal permeability, so maybe Sparrow is right, and your immune system has become more sensitive.

    You may need to work on your gut some, such as by running a comprehensive stool test to see what's going on there in terms of bacteria, yeast, and/or parasites, and treating what needs to be treated to lower the intestinal permeability. The Metametrix G.I. Function profile looks for all of these guys using DNA analysis. It can be ordered through some doctors, or from www.directlabs.com without a doctor's order.

    In the meantime, you might consider rotating foods, like on one week and off one week.

    Best regards,

    Rich
     
  4. undcvr

    undcvr Senior Member

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    Stop the methylation protocol. Eat more fiber/pectin foods to move toxins out of your body. 3 apples a day for a week.
     
  5. fozzaw

    fozzaw

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  6. maryb

    maryb iherb code TAK122

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    I was in a bad place a couple of weeks ago too, couldn't tolerate any form of protein after doing quite well for a couple of years, a kind person on PR told me about an a/histamine called Zirtek, the active ingredient is cetirizine hydrochloride, Piriteze is the same product too. I started with 1/2 a tablet and made sure someone was around when I took it, always best for those of us with severe allergies, apart from a dry mouth I was fine, and now take 1/2 twice a day, have been able to intoduce meat back into my diet slowly, I can tell my allergic responses are lessened in general. Its not a cure but if it helps get you over this blip then maybe think about trying this or another one, its one of the non sedating ones.
    Also maybe lower the methylation doses too until you get to a plateau again?
     
  7. nanonug

    nanonug Senior Member

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    Isn't methylation necessary to metabolize histamine? If this is so, it would suggest that increasing methylation would lead to lessened allergic response. However, if the person is using folic acid, that could be the problem right there (I actually couldn't see the post on curezone, for some reason.)
     
  8. fozzaw

    fozzaw

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    Which methylation steps should be increased?
     
  9. triffid113

    triffid113 Day of the Square Peg

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    YES! This is just what I would have said only with more detail. However I would go one further (and I don't know if this would work for everyone) but when I had gut permeability, it was cured by taking more ZINC. It takes zinc to make skin. If you do not have enough zinc, your skin will have larger pores as the body spreads out the zinc. Anyway, this is the explanation given for why zinc prevents colds and I figure the gut lining is ALSO SKIN. Anyway, it worked for me.

    Take care
    Triffid
     
  10. triffid113

    triffid113 Day of the Square Peg

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    This may be true for this person, but I will tell you that *I* always have too much histamine and neither more nor less methylation does anything for it. The only thing that methylation does for me allergy wise is stop insect bites from itching. I still get horrific spring and fall allergies. I do not have appreciable food allergies (but I used to have a bad one to wheat and I *knew* I could cure it because I hadn't always had it....zinc is what did it for me). I would say I am still allergic to wheat but that I am mostly desensitized to it (what I mean is that with stress or poor diet the allergy will spring right back). Also I want to point out that allergies are cumulative so (and this is not a cure but a management strategy) if you elminate any other allergens and if that is not enough STOP whatever food item is bothering you for 1 week or so, you can usually go right back to your (bad) habits until next time (which may be only 2 weeks away, but - hey - you've had a normal life for 2 weeks on then not-so-normal for 1 week, a 66% improvement).

    Triffid
     
  11. nanonug

    nanonug Senior Member

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    Well, if the person has certain MTHFR mutations, the use of folic acid would be a mistake. Methylfolate would have to be taken instead.
     
  12. fozzaw

    fozzaw

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    When you said more or less methylation, which steps specifically are you referring to? Because methylation has many steps that you can manipulate.
     
  13. fozzaw

    fozzaw

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    So you are saying that supplementing methylfolate should reduce histamine levels?
     
  14. nanonug

    nanonug Senior Member

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    I am saying that if there are methylation issues due to MTHFR mutations, supplementing with methylfolate instead of folic acid, in appropriate amounts, has a good chance of dealing with excess histamine.
     
  15. adreno

    adreno 3% neanderthal

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    But the OP is already supplementing methylfolate, which has only increased histamine (which is why this thread was started).
     
  16. richvank

    richvank Senior Member

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    Hi, all.

    A couple of points:

    It's important to distinguish between food allergies (which involve IgE antibodies and histamine produced in the body, and are often permanent) and food sensitivities (which involve "leaky gut" and IgG antibodies and are temporary, so that they go away when the provocative food is withheld). There are also food sensitivities to foods that contain histamine themselves.

    Histamine is metabolized intracellularly by a reaction that requires methylation. Extracellularly, which is particularly important for controlling symptoms, histamine is normally metabolized by diamine oxidase, which requires P5P and copper. There is an over-the-counter product called Histame (or Daosin) which augments the action of diamine oxidase and may help with food reactions that involve histamine for people who do not have sufficient diamine oxidase function.

    Best regards,

    Rich
     
  17. chilove

    chilove Senior Member

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    That's what I thought! I'm not taking any form of folic acid.. only methyl folate.
     
  18. chilove

    chilove Senior Member

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    I was also suspecting the immune system being overburdened with increased detoxification theory.. I just don't know for sure though...
     
  19. chilove

    chilove Senior Member

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    "Well, if the person has certain MTHFR mutations, the use of folic acid would be a mistake. Methylfolate would have to be taken instead. "

    I do have MTHFR mutations and am only taking methyfolate.
     
  20. chilove

    chilove Senior Member

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    Hi all

    Thanks so much for the responses.

    I tested very high in copper and low in zinc. I agree with Rich that it could be leaky gut as I've suspected that in the past but I can't seem to fix it. I've tried several products for it already in the past. I've been taking 30mg of zinc per day for about the last two months.. Maybe I need more

    I'm seriously about to go crazy with the sensitivities... I already had a very limited diet (raw fruits and some veggies) and now I'm reacting to any fruit that is brightly colored so I'm suspecting its something to do with the colors...

    I'm underweight and have adrenal issues and need to support my body with more nutrition but I have no idea what to try to eat that wont make me feel horrible.

    I'm curious to try the Zyrtec for a temporary respite.. I'll also check out the Histame Rich...

    Thanks so much!

    Audrey
     

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