Hi, I got my testing done. I just downloaded "Start Low and Go Slow" and read thru it and have been doing a lot of reading online. I'm 42, on syn thyroid and have CFS. Always had trouble losing weight although I did manage to lose it all at one point and kept it off for 2yrs before it all came back. Here is my 23 and me reading: Homozygous COMT V158M rs4680 COMT H62H rs4633 VDR TAQ rs731236 MAO-A R297R rs6323 MTRR A66G rs1801394 Heterozygous MTHFR A1298C rs1801131 AHCY-01 rs819147 AHCY-19 rs819171 CBS C699T rs234706 CBS A360A rs1801181 After reading a lot of Yasko and other resources it sounds like I should be taking the following: - Hydroxy B12 and or Adenosyl B12 - Folate - Potassium - Grapeseed Extract - GABA - SAM-E - Molybdenum Should I also be taking TMG? I already take some other vitamins (fish oil, D3, magnesium, etc.). What do you guys think of this? http://www.blackbearb12.com/energy-redefined/ingredients/ It's listed on holistic heal. What are some good brands for vitamins? I've had very good experiences with Jarrows and Thorne Research but they don't seem to have hydroxy forms. My biggest concern is getting the co-factors for B12 figured out right - it seems like I will need Potassium and also Folate. Is there anything you think I'm missing?