Jesse2233
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At the OMF symposium, Drs Alan Light and Jonas Bergquist both independently confirmed the presence of adrenergic and muscarinic receptor autoantibodies in their patients (vs controls). Although their studies have yet to be published, their research effectively replicates that of Dr Carmen Scheibenbogen and indicates an autoimmune etiology.
Of course other autoantibodies have shown up in previous studies, and there's still the issue of a chronic pathogen / dysbiosis potentially causing these autoantibodies (and the downstream effects on cytokines and metabolism).
But adrenergic and muscarinic receptor malfunctioning can plausibly explain many of the core orthostatic and neurological symptoms.
The good news here is that autoimmune treatment protocols should apply well. This seems to be true given the reports from Scheibenbogen group showing improvement following immunoadsorption and IVIG, and Fluge / Mella's trials of Rituximab and Cyclophosphamide.
From Dr Light's slides:
From Dr Bergquist's slides:
And from Dr Scheibengoen's study:
Of course other autoantibodies have shown up in previous studies, and there's still the issue of a chronic pathogen / dysbiosis potentially causing these autoantibodies (and the downstream effects on cytokines and metabolism).
But adrenergic and muscarinic receptor malfunctioning can plausibly explain many of the core orthostatic and neurological symptoms.
The good news here is that autoimmune treatment protocols should apply well. This seems to be true given the reports from Scheibenbogen group showing improvement following immunoadsorption and IVIG, and Fluge / Mella's trials of Rituximab and Cyclophosphamide.
From Dr Light's slides:
From Dr Bergquist's slides:
And from Dr Scheibengoen's study:
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