A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
Mark Berry presents the first in a series of articles on the 11th Invest in ME International ME Conference in London ...
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Has anyone tried Deplin?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by anniekim, Jun 29, 2012.

  1. anniekim

    anniekim Senior Member

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    Dr D-J in Hawai seems to be having success with some patients trying deplin. Has anyone tried it? And if so, any benefits or negatives? Many thanks
     
  2. arx

    arx Senior Member

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    Isn't Deplin the same as Metafolin (L-Methylfolate) ?
     
  3. anniekim

    anniekim Senior Member

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    Yes, but in much higher doses. Although Dr D J has said that in clinical practise she does feel there is a difference. I should note that I've tried a low dose 200mcg of methylmate and can only tolerate it every other day or even every three days. I think i read somewhere that even if only tolerate small amounts for some reason which I don't understand i might nonetheless tolerate a much higher dose in the form of deplin. Can anyone explain why this would be? Many thanks
     
  4. arx

    arx Senior Member

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    From what I have gathered,people on this forum usually take 800mcg of metafolin in a day.

    Freddd has said that the side effects on Deplin research state "Deplin is generally well tolerated with no side effects different from placebo". (Refer to http://forums.phoenixrising.me/index.php?threads/active-b12-protocol-basics.10138/)
    I started getting headaches after taking one Deplin(7.5mg) everydy for a month,so I broke the tablet into around 8 parts and now I take 1/8th of 7.5mg everyday, which is around 800 mcg only. I no longer get those headaches.

    I'm sorry but I have no idea about methylmate.What is it?
     
  5. anniekim

    anniekim Senior Member

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    Thanks arx. Methylmate B is another name for metafolin, it's the same.
     
  6. arx

    arx Senior Member

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    Oh ok. You're welcome. :)
     

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