Mine aren't as bad as they used to be, but they're far from gone. I suspect that erratic sleep is the biggest contributing factor at the moment. Changing my anti-seizure med from Tegretol to one that is also a dopamine enhancer helped a lot. (Maybe I can remember name of med next time I'm here!) What helps you most? I posted this here because I know lifestyle management plays a big part - too little energy for emotions when utterly exhausted. i'd like to know what helps you, whatever it is. ps The other day someone (not a PWC) assured me that SAMe would take care of my sleep problems. I didn't bother telling her just how high a dose I used to take!