Background - I got gradually ill, with my illness slowly progressing from normal functioning, through moderate and finally to severe between 2009 and now. The only strange thing I can remember about my health from the time I got ill is a large patch of cold sores from my nose to my top lip on one side. It was there for about 5 or 6 months before it healed. I was ill with suspected swine flu in 2010, but had already been diagnosed with ME/CFS beforehand. In 2014 I had a major, full face flare up of cold sores, was on acyclovir tablets until a few months ago to keep them at bay. No improvement in ME symptoms while on acyclovir. Attached pic of 2014 cold sores to illustrate the severity.