Has anyone ever taken Nuvigil? I'm 16 months into a depression, having tried all the latest and greatest medicines to no avail. One day my doctor handed me a sample of Nuvigil (200mg). I didn't think much of it, just something else that won't work. He said it may act quickly (a stimulus). I went home and lay down and in 20 minutes, I couldn't believe it! I wasn't 95% my old self...I was 100%! I just couldn't believe it. I ran around town talking to people, went back over and hugged the doctor. But then gradually, about 3 hrs. later I began to feel it slowly wear off...until it was completely gone, and back in the dumps. The amazing thing, never has it made me feel that way again (100%), and when I take it I only feel like it gives me 20-30% help. So if you're thinking about trying it out yourself, hope your doctor has some free samples. It's $600! P.S: I don't know how this whole thing works...can someone explain what a thread etc. is.