Mine is particularly bad unless I take low dose klonopin and one pill of florinef. Just florinef without the klonopin has a tendency to give me chest pain, which is not good. Also I need to add salt intake to the daily dose of florinef. Mine is orthostatic hypertension. Thank you in advance for your input. There seems to be two primary variations of this (correct me if I'm wrong) - one involves an imbalance in adrenaline/noradrenaline receptors or amount of adrenaline/noradrenaline and the other possibility is low blood volume. But then I should add a third - electrolyte imbalance, which would be best treated with florinef if aldosterone is low. Which one of it do you guys have? The first treatment would involve either a beta blocker or norepinephrine reuptake inhibitor from my understanding of the scientific literature. The second, low blood volume, would involve adding possibly desmopressin or florinef. The third - an electrolyte imbalance, would I guess depending on if it was too much sodium or too little sodium involve a diuretic or florinef. This is the gist of what I am seeing. And of course there is just all out hypotension in orthostatic intolerance - low blood pressure - which I would assume florinef or cortisol replacement could remedy. I am just curious how many of you have what form of this. I figure if we can break down a % of us that have tried each treatment and correlate our symptoms - we can better ameliorate the symptoms of this horrible thing. For me personally - my systolic, diastolic, and pulse rate will raise dramatically upon sitting and standing up. Upon lying down immediately it would fall back to normal 120/80 with a 75 pulse rate. Standing or sitting up it could go as high as 160/120 with a 110 pulse rate in a matter of seconds. It is very hard for me to think that adrenaline can be secreted that quickly if that is the true cause, and somehow the adrenaline is detached from the receptor or the receptor is inactivated upon lying down in a matter of seconds. And with standing or sitting comes the dizziness. In trying desmopressin there was no change at all. Loading up with fluid made absolutely no difference, in fact it may have made it worse by diluting electrolytes even further. Florinef seems to help the most. But Florinef has a tendency to make my heart pound harder and raise BP/pulse. I have tried serotonin reputake inhibitors and really the best treatment for me seems to be a combination of low dose klonopin and one pill of florinef. A saline IV also made me feel better in the ER several times. This gets tricky though. I have a test showing my ADH was in the upper range. I know in hypoaldosteronism that ADH can rise consistently. Just curious on what your experiences on this are. There are a ton of threads stating different symptoms and whatnot but I think if we can get everyone in one thread to state their story and treatment attempts and possibly successes we will all immensely benefit in this sub forum.