Has an 8 Year-Old Girl Discovered a Treatment for Cancer

[natasa778]

Lisanti reports that it’s a well-known side effect for antibiotics to target the mitochondria in human and animal cells [1]. His explanation for the success of these early trials is the fact that mitochondrial numbers tend to vary by cell according to the rate of the cell’s proliferation. Rapidly dividing cancer cells, for instance, have very large numbers of mitochondria because mitochondria supply necessary energy for the cell. Therefore, cancer cells are particularly vulnerable to mitochondrial impairments and thus antibiotic exposure. ...

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Lisanti and his team studied 5 different classes of antibiotics which are known to target mitochondria. Each of these classes acts by inhibiting protein synthesis in mitochondria through different targets (e.g., the 39S large mitochondrial ribosome versus the 28S small mitochondrial ribosome, etc.), while leaving protein synthesis in the cytoplasm of the cell unaffected. They found, for instance, that the broad-spectrum antibiotic, doxycycline, inhibited tumor-sphere formation across a variety of different cancer types tested, including breast, ovarian, lung, melanoma, prostate, and pancreatic cancers.

Currently, there are two clinical trials initiated or ongoing to test the efficacy of antibiotic use on cancer treatment. One clinical trial, which has already moved into Phase 2, is testing doxycycline use on advanced breast cancer and bone metastasis. And another study, which is still currently recruiting patients, is testing doxycycline use in relapsed patients with non-Hodgkin’s lymphoma, which can be accessed here for anyone interested ..

http://scienceoveracuppa.com/2015/0...r-old-girl-discovered-a-treatment-for-cancer/

 

[Martial]

one infection that has implications in various types of cancer, as well as reversing the process with antibiotic exposure is Mycoplasma bacterium. I just hope they do not use any type of quinoline based antibiotics for these trials.