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Gut microbiome - Vibrio and Legionellaceae

Discussion in 'Gastrointestinal and Urinary' started by olliec, Nov 14, 2015.

  1. olliec

    olliec

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    London, UK
    I just got my results back from the British Gut Project (linked to the American Gut Project) to sequence my gut microbiota. I've done it with uBiome before. Two results stand out. One is that my levels of family Legionellaceae are 179x the average, and genus Vibrio is 41x average.

    I read about the groups of bacteria and it looks like vibrio is shellfish food poisoning bacteria, which is intriguing to me as I have an allergy and don't eat shellfish. The other group's main members are legionella and coxiella burnetti (Q Fever). These are not viruses but bacteria so I do not think this relates to John Chia's work. I expect the result means probably either Coxiella or Legionella is present. I'm aware Q Fever is a known trigger for ME, but what is it doing in my gut?

    I am moderately affected, but when I really overdo it (especially physically) my symptoms rapidly deteriorate into more obvious flu-like symptoms, including what certainly looks like a chest infection. I can't help but wonder if this pattern is potentially some chronic, latent infection (Coxiella) reactivating. Might I have found it? But I've no reason to know whether the presence of bacteria is a cause or just another symptom. Maybe a messed up immune system allows it to flourish.

    I asked Tim Spector on Twitter (who runs British Gut project, and wrote the excellent book The Diet Myth) if I should be worried and he said "Sounds a bit worrying but worth talking to somebody and repeating test". I am a patient at the Royal Free and am seeing an immunologist there in December, but wanted to learn more about what this might mean before I go. I need to re-run the test to check the result.
     
    Theodore, merylg, Hutan and 1 other person like this.
  2. msf

    msf Senior Member

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    I don´t know much about those genuses of bacteria, but if they seem to be pathogenic ones then I wouldn´t listen to anyone who tries to ignore or shrug off the result. If I was you I would look into testing for the species of bacteria you mentioned.
     
  3. olliec

    olliec

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    London, UK
    It's difficult to deduce much from the test result as firstly it's not been repeated (it may be wrong), but secondly that the results only show the group, so I have no idea if it implies Coxiella or Legionella (or even both). The test isn't specific enough to be of much use, but it at least shines a light on an area to look at.
     

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