• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

Gut controls brain inflammation (Multiple Sclerosis)

msf

Senior Member
Messages
3,650
I would say it is quite likely that something similar is happening in ME. Dr. Hornig said something about very low levels of serotonin being found in the short-term ME group, perhaps this ´tryptophan-derived product´ is also low in people with ME.
 

msf

Senior Member
Messages
3,650
I found this video of Hornig talking about tryptophan, etc in ME (26.30-31.00):

She seems to be suggesting that the problem in people with ME is that a pro-inflammatory response is causing the serotonin pathway to become dysregulated.