The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Gut bacteria linked to multiple sclerosis

Discussion in 'Other Health News and Research' started by Sidereal, Sep 21, 2017.

  1. Sidereal

    Sidereal Senior Member

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    https://www.nature.com/articles/d41586-017-03639-3?WT.mc_id=TWT_NA_1709_RESEARCHIGHLIGHT_PORTFOLIO

    Tregs and IL-10 showing up again. (cc: @nandixon @adreno )
     
  2. lafarfelue

    lafarfelue Senior Member

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  3. adreno

    adreno PR activist

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    This is close to what I believe happens in ME. Dysbiosis, perhaps combined with genetic dispositions, plus an environmental insult (trigger).
     
    jpcv, Forbin and Sidereal like this.
  4. Sidereal

    Sidereal Senior Member

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    Interesting to see an increased prevalence of the mucin-degrading Akkermansia in MS patients. A few years ago when potato starch and prebiotics were all the rage, some paleos were promoting this bacterium as a sign of great gut health & good for weight loss.
     
    Thinktank likes this.
  5. adreno

    adreno PR activist

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    I read on cfsremission that akkermansia is generally low in ME.
     
    Sidereal likes this.
  6. adreno

    adreno PR activist

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    Lately I have been thinking that ME is sort of the opposite of MS. So if a treatment is recommended for MS it is probably crap for ME.
     
    halcyon likes this.
  7. alicec

    alicec Senior Member

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    I think it is a sign of good gut health and indicates good mucosal barrier function.

    Too much though can lead to erosion of the mucous barrier.
     
  8. bertiedog

    bertiedog Senior Member

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    In my recent American Gut results Akkermansia was the 7th most predominant bacteria in my gut but only at pretty low levels 0.75%. Dr Michael Mosley in his book called The Clever Guts Diet is all for increasing this bacteria in the gut because it is associated with less obesity btw.

    Pam
     
  9. adreno

    adreno PR activist

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    I just got my results from uBiome, and they are:

    Akkermansia: 1.30 X
     
    bertiedog likes this.

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