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Gut bacteria can cause, predict and prevent rheumatoid arthritis

Discussion in 'Other Health News and Research' started by A.B., Jul 12, 2016.

  1. A.B.

    A.B. Senior Member

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    https://www.sciencedaily.com/releases/2016/07/160711151315.htm
     
  2. Gemini

    Gemini Senior Member

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    Sidereal and Effi like this.
  3. Effi

    Effi Senior Member

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    Not sure if this has been posted somewhere, but here's a recent small study about the microbiome in MS: http://www.nature.com/articles/srep28484

     
    actup, TigerLilea, aimossy and 2 others like this.
  4. Gemini

    Gemini Senior Member

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    Thank you for posting this Mayo Clinic study @Effi. Very detailed & interesting.

    Excerpts:

    "Metabolites derived from the metabolism of phytoestrogens...and bile acids play an important role in maintaining homeostasis at the mucosal surfaces through the induction of anti-inflammatory responses."

    "When combined with the fact that RRMS patients have reduced levels of bacteria responsible for metabolizing phytoestrogens, this might implicate regulation of estrogen receptor signaling by gut microbiota and/or their metabolites in the etiopathogenesis of RRMS."

    "The abundance of microbes involved in the phytoestrogen metabolic pathway is interesting as there is increased female prevalence in MS."

    "Large studies that include time series of samples and methodology to study the functional changes in the intestinal microbiota are needed for the evaluation of the role of gut microbiota in the modulation of immune system response."

    Perhaps with Dr. Nath's and NINDS expertise along with increased NIH funding Dr. Lipkin and others will perform large microbiome studies for us.
     
    MEMum and aimossy like this.
  5. Nielk

    Nielk

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    Why assume that this is a causal effect as opposed to a result from chronic inflammation in the body?
     
    Art Vandelay and roller like this.
  6. roller

    roller wiggle jiggle

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    all diseases may change the microbiome.

    the changes would be logical anyway, when assuming that the classic way of falling sick is due to bug/parasite/pathogen infestation.

    so sad, how they are staggering through the fog.
    im wondering, if their brain fog/mental handicap isnt worse than ours.
     

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