Behav Brain Res. 2009 Jul 27. [Epub ahead of print] Links Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and Biochemical Evidence. They basically gave these mice what they believe is chronic fatigue syndrome by injecting them with lipopolysaccharides - which are, as I remember, bacterial toxins. After they did this the mice had increased fatigue, less mobility, etc. and increased oxidative stress and increased pro-inflammatory cytokine production. Simply by giving the mice epigallocatechin gallate the mice recovered from their reaction to the pathogenic toxins; their fatigue disappeared in the size of oxidative stress and inflammation did as well. Another study found that it increased endurance in fatigued mice as well. http://www.ncbi.nlm.nih.gov/pubmed/18455659?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Epig....gallate is found in Green tea extract. Interestingly given our recent discussion of mesenchymal cells and Dr. Cheney's use of them epi...gallate has been shown to possibly increase the viability of those treatments. http://www.ncbi.nlm.nih.gov/pubmed/19640263?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum This study notes that the bioavailability of epi...gallate is generally low but that it can be boosted with quercetin and red onions(!)(?) http://www.ncbi.nlm.nih.gov/pubmed/19585479?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Anyone ever try green tea extract?