I am interested to know if anyone else has had both conditions? My energy levels were, unsurprisingly, significantly improved when I was hyperthyroid. Taking the meds to lower my thyroid levels, and being inadequately monitored (in my opinion) led to me becoming temporarily hypothyroid. My ME was exacerbated considerably and I have never recovered. One of the reasons I am asking now is that I have just read an abstract about successful treatment of the TSH antibodies in Graves with Rituximab.... Those pesky B cells again!