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Grape seed extract, reasons for getting bad?

Discussion in 'General Treatment' started by Sinclair, Nov 26, 2014.

  1. Sinclair

    Sinclair Senior Member

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    I recall eating grape seeds experiencing some improvement.:)

    However after a few days trialing grape seed extract (GSE) I think this might be the cause of the recent worsening of my symptoms. It don't appears as a die-off to me, but as an agent working against my efforts towards generating a Th1 response (steps back feeling)

    I was wondering if anyone has had bad experiences with GSE, or would be so kind in explaining me the likely causes for a bad reaction.

    Many thanks in advance!

    S.
     
    Last edited: Nov 26, 2014
  2. maryb

    maryb iherb code TAK122

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    Is it grapefruit seed or grape seed? they are very different, grape seed is an antioxidant, the other is a cyst/biofilm buster used in Lyme treatment.
     
  3. Sinclair

    Sinclair Senior Member

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    Grape Seed Extract
     
  4. Ema

    Ema Senior Member

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    Grape seed extract promotes a Th1 response.

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC119947/
     
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  5. maryb

    maryb iherb code TAK122

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    Very interesting article thanks @Ema
     
  6. Sinclair

    Sinclair Senior Member

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    Thanks for your replies:thumbsup:

    And it is recommended for leaky gut as well.

    I tried it for both reasons, however I felt bad on it.....could this be due to low oxygen at the cellular level or lack of something else playing as co- factor?
     
  7. Gondwanaland

    Gondwanaland Senior Member

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    What do you feel?
    What else do you take?
    What I know about Grape Seed Extract is that it is high salicylates and estrogenic.
     
  8. Sinclair

    Sinclair Senior Member

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    Basically, I feel that the improvements I get with the protocol listed in my signature become less strong, I start to feel again symptoms that were "under control", such as pain in my spine and abdomen and increased weakness. As if GSE was acting in the opposite direction....I don't know how to describe it in more details...

    What consequences or symptoms may be expected from high salicylates or estrogenic GSE's properties?

    Thanks @Gondwanaland!
     
  9. Helen

    Helen Senior Member

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  10. Gondwanaland

    Gondwanaland Senior Member

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    Sorry, I didn't notice your sig before

    I have experienced high salicylate symptoms as increased uric acid, increased ammonia, MCS (toothpaste!), sudden several food intolerances (essentially breathlessness).

    I reversed it with a couple of sodium bicarbonate baths and one month of aggressive oral magnesium supplementation. Due to increased uric acid I don't think I would tolerate Mg chloride, and due to increased ammonia I never tolerated Mg sulfate (Epsom salts).

    I understand that due to your condition you wouldn't tolerate oral magnesium...

    But for you it could be something else.
     
  11. Gondwanaland

    Gondwanaland Senior Member

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  12. Sinclair

    Sinclair Senior Member

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  13. Gondwanaland

    Gondwanaland Senior Member

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    Grape Seed Extract pools with vit E increasing the blood thinning effect.
     
  14. Helen

    Helen Senior Member

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    :)
    In fact, I thought more of the risks for you if you have mutations in the CYPs that were mentioned ("detox genes" if you have a 23andme test result)
    Grape fruit juice e.g. is wellknown in medicine to affect the metabolism of lots of drugs even without gene defects in the CYP3A4.
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1873672/
     
  15. Sinclair

    Sinclair Senior Member

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    Thanks @Helen and @Gondwanaland.

    It seems hard to discover the reason without further tests... I plan to have them by January...meanwhile, there is not that much I can do from my country beyond stopping GSE intake....
     
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