A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
Mark Berry presents the first in a series of articles on the 11th Invest in ME International ME Conference in London ...
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Glycine/Serine ratio and under/over methylation?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Kimsie, Feb 10, 2016.

  1. Kimsie

    Kimsie Senior Member

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    Could the Glycine/Serine ratio could tell us anything about whether a person is over/undermethlyated? I don't think it could be used all by itself, but along with other factors it might give evidence for a person to figure out if they are an over or under methylator.

    Here are the NutrEval results for me and my husband.
    Glycine_serine ratio.jpg
    The ratios go along with what I have suspected to be our methylation type. I think the angle of the red line is more important than the ratio numbers.

    A person could have a high or low ratio and have normal methylation, since so many factors are involved, but if a person has reason to believe that their methylation is not normal, the ratio could give a clue because glycine is used to keep SAMe levels from getting too high, and the glycine/serine ratio affects the direction of the SHMT enzyme which affects the availability of 5, 10 methyleneTHF, which is needed for MTHFR and for thymidlyate synthesis.
     

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