Hi Everyone, I don't have CFS, but got attracted to this forum by high quality posts. I would to learn more about glutathione, how it is produced and recycled. A few months ago I ran a spectracell micronutrient tests which told me I am desperately low in antioxidant function. I was supposed to supplement NAC among others, but I actually started with reduced glutathione with good results, some health problems resolved. After learning that glutathione is actually hydrolized to the three constituent amino acids on digestion, and getting additional glutamate might a be a bad idea, I switched to NAC. I also saw someone saying to supplement glutamine and glycine and rely on homocysteine for cysteine. I have elevated homocysteine so that rings true. Where can I learn more about this? I would also like to find out why would glutathione be low with high homocysteine at the same time and CBS upregulation (lack of some substrates/co-factors?).