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H

Helen

Senior Member
Messages
2,243
Thanks @PeterPositive for the correct link. Last weekend I listened to a talk about " Genetic variation in detoxification" and the professor that lectured mentioned grape fruit juice and milk thistle as two things among others to be careful with not to lower the detoxification in Phase I.

If substances proceed undetoxed to Phase II (due to too low enzyme activity for some reason-s) , more toxins than before might be present.
 
M

Mels

Messages
88
Location
Oxfordshire, UK
Those with CBS issues need to be careful with Milk Thistle as it is high sulphur(or thiols?) It messed me up for months last year..........Also high in salicylates for anybody who has trouble with them. Seems to me that a lot of the liver support supplements are tricky for us CBS people. Anybody know a good one that is low salicylate and low thiol? Or am I asking for the earth?!
 
PeterPositive

PeterPositive

Senior Member
Messages
1,426
Helen said:
Thanks @PeterPositive for the correct link. Last weekend I listened to a talk about " Genetic variation in detoxification" and the professor that lectured mentioned grape fruit juice and milk thistle as two things among others to be careful with not to lower the detoxification in Phase I.
Click to expand...
It's an interesting idea but I am not sure if the evidence is really strong for it. The cited paper is from 2000 while the review I posted is from 2013 and doesn't seem to really support the findings. Do you know of more sources that corroborate the hypothesis?

Also, has anyone tried Desmodium for liver detox/support?
 
H

Helen

Senior Member
Messages
2,243
PeterPositive said:
It's an interesting idea but I am not sure if the evidence is really strong for it. The cited paper is from 2000 while the review I posted is from 2013 and doesn't seem to really support the findings. Do you know of more sources that corroborate the hypothesis?

Also, has anyone tried Desmodium for liver detox/support?
Click to expand...

I crashed after attending the meeting with the actual talk so I am not able to go into details about studies on this issue. I just wanted to forward the doubt of using milk thistle, particularly if you would have gene defects of importance in Phase I ( the SNP´s named as CYP in e.g. a detox panel) . FWIW. I am sure you will find out if milk thistle is beneficial for you or not.
 
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