The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
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Glutamine creating severe Brain fog

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by Viking, Sep 14, 2015.

  1. Viking

    Viking

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    Hello all,
    I used Glutamine ( 2500mg twice a day) for about 8 days to help with bowel repair after a parasite infection, and developed severe brain fog. It has persisted for weeks even after discontinuing.
    I have a number of methylation snps that I suspect may be related, but am not sure. (CBS699 + - and a number of BHMT++ snps)

    Has anyone else experienced this or found a way to resolve it?

    Regards,
    Viking
     
  2. LivingwithFibro

    LivingwithFibro Lily

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    Maybe the dose was too high? I hope you feel better soon! :( I had brain fog due to the same dose of Nac but it cleared up after a while...I know it's not the same thing though.
     
  3. Mary

    Mary Senior Member

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    Glutamine (and other things) caused a detox reaction for me, which I associated with mercury. It made me spacey, had difficulty concentrating, tired, etc. It is used in Phase II liver detoxification. My symptoms went away when I cut my dose, but I didn't take as much as you - I was taking 1000 mg. a day. I don't know if this is what you are going through. It also is possible that the NAC reaction Livingwithfibro had was also due to mercury toxicity.

    Here's a good article about supplements which are needed for Phase I and II liver detox:
    http://www.diagnose-me.com/treatment/liver-detoxification-phase-II-support.html

    Almost anything involved in liver detoxification initially caused a detox reaction for me. I eventually became able to tolerate glutamine (as well as glycine and inositol), it seemed somehow I got rid of my mercury burden.

    But I don't know if mercury toxicity has anything to do with your brain fog - I hope you get some answers!
     
    LivingwithFibro likes this.
  4. Ema

    Ema Senior Member

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    I would consider trying ammonia reducing supplements like yucca.
     
  5. LivingwithFibro

    LivingwithFibro Lily

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    I don't have mercury issues, well, none that I know of but I am going to take ALA frequently at a low dose every 3 hours and see if the brain fog issue clears up. If not then it's due to something else I guess. It doesn't happen on 600-1800 mg of NAC but on 2400 mg.
     

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