Hello all, I am new here and have a question. I will introduce myself later when I have more time but i have a burning question regarding the methylation pathway and Yasko's work. She suggests that glutamate is an excitotoxin and that fits with my experience of anxiety, heart palpitations etc. within moments of eating trigger foods, which are many. Certainly food sensitivities are part of the picture and I have done extensive work around them. But the continue to spread. I have been feeling some relief in finding a theory and maybe an approach that fits my experience (almost 20 years). Now I am disturbed and confused about a recent development. As part of my gut repair program with local CFS Doc, who is not very familiar w Yasko's work, I am taking 500 mg glutamine along w slippery elm and marshmallow root 2x/day and tolerating it well. They seem to be having a soothing and healing effect on my digestion w out any neuroexcitement. How does that make sense since glutamine is a form of glutamate. ( I just discovered) Any thoughts would be welcomed. I know the picture is more complex than I would like it to be. Any clarity is welcome. thank you Lucy H. PS I wonder if others find relief in avoiding glutamate rich foods or if this is more a part of the autism protocol and not necessary for CFS'ers.