Hi Mij Close, 21 years for me I get a REALY bad headache and my eyes turn red with a sick/nauseated feeling. I can only tolerate about 15mgs of any form from a capsule/tablet Zinc carnosin, a slightly higher dose Liquid Zinc up to 100mgs with NO reaction at all - this also boosted Testosterone levels after 6weeks and was the ONLY form to increase plasma Zinc concentrations I am yet to experiment with 6x HCL and pepsin with a full dose of Zinc in tablet/capsule form. Too afraid though I have been on porcine Digestive Enzymes for over a decade which do very little, after adding the HCL with Pepsin the difference has been INSAINE! Like I described to Hip, McBride has stated in her book Gut And Phycology Syndrome that pathogens in the Gut drastically reduce HCL levels, she also explains how important proper HCL levels are at setting up the digestive cascade of events, even how proper levels promote the release of pancreatic enzymes. I HIGHLY simplified what she describes in that chapter of her book. You need to take enough HCL with pepsin to notice the difference, some have described taking enough when they feel 'warmth' from there stomach. Once again that description is highly simplified - research it. Hmmm I really struggle to understand some times why some things work in some and not others. Dr Chia has found only 51% respond to Oxymatrine... Would LOVE to know exacterly why there are non responders? Like I described on another thread Epicor and a Mushroom complex(both Th1 promoters)gave me DRASTIC side effects! -Headache -Dizzyness -Cramping tight muscles in neck So, I expect to be hit by a truck with this Oxy/Inosine combo??