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Genetics Link Sleep Disturbances With Restless Leg Syndrome, Schizophrenia and Obesity

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AndyPR

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The researchers identified for the first time areas of the genome that are associated with sleep disturbance – including insomnia and excessive daytime sleepiness – and also discovered novel genetic links with several medical conditions, including restless legs syndrome, schizophrenia and obesity. The strongest genetic association for insomnia symptoms fell within a gene previously linked to restless legs syndrome – a nervous system disorder affecting around 1 in 20 people that leads to a strong urge to move one’s legs, which is often worse at night. Other gene regions were important for insomnia, but selectively in either men or women.

The team also identified genetic links between longer sleep duration and schizophrenia risk and between increased levels of excessive daytime sleepiness and measures of obesity (body mass index and waist circumference). The research also suggested that insomnia has shared underlying biology with major depression and abnormal glucose metabolism.
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Full paper talks of "impaired glucose tolerance", so I would guess not the same issues that we seem to have.

http://neurosciencenews.com/sleep-genetics-obesity-schizophrenia-5776/

Full paper at http://sci-hub.cc/10.1038/ng.3749
 
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