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Genetic Genie Reports - request for assistance please

Discussion in 'Genetic Testing and SNPs' started by vlc, Apr 29, 2016.

  1. vlc

    vlc

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    If any experienced members can find the time to help me better understand my Genetic Genie reports I would be most grateful. I'm rather overwhelmed with the information presently.
    Thank you!
    genetic genie methylation.PNG

    [/ATTACH] genetic genie detox.PNG
     
  2. alicec

    alicec Senior Member

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    Australia
    There's very little there of any concern.

    The ones that do something are

    MTHFR A1298C, +/-, a very small slowing of the enzyme. A small dose of methyl folate could be helpful, plus the cofactor for the enzyme vit B2.

    MTRR A66G and K350A both slow the enzyme, but +/- would have a small effect. A small dose of methyl B12 could be helpful.

    The MAOA +/+ means nothing in itself but there are a lot of confusing claims about it. Here is a post about that SNP.

    Some of the flagged detox SNPs do have a small effect but it is often combinations that are relevant.

    I suggest you run your results through Promethease which has a much more extensive analysis and does deal with some of the detox combinations.

    Here is a recent thread which gives some perspective on SNP analysis.

    There are lots of threads about different SNPs. Just search on the genetic analysis forum.
     
    Last edited: May 6, 2016
    Valentijn likes this.
  3. JES

    JES Senior Member

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    You only have two homozygous SNPs (marked red), congrats! It's probably the lowest I've seen from screenshots posted here (I have 9). The only thing I would look at is MTHFR A1298C and even that is not as much of a concern as it's heterozygous, apparently some 40% of population has this. But a small dosage of methylfolate could be trialed.
     
    Penn likes this.
  4. vlc

    vlc

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    Thank you both for your responses.
     

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