I took IVIG for a few months. It made me feel really overstimulated/agitated. Made my sensory hypersensitivity/irritability worse. It took a couple weeks for this effect to wear off after each infusion. It also made my cytokines go up. Ultimately, I stopped doing it. I don't think I am any worse or better in the long term from taking it, but it was a bit uncomfortable after each infusion. I haven't met anyone else with this response and my doctor was kind of confused. I took gammunex 10g every 2 weeks (iirc).