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G.I Results Panel

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by Ben H, Mar 29, 2013.

  1. sianrecovery

    sianrecovery Senior Member

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    Manchester UK
    interesting paper that MeSci, thanks.
     
  2. aquariusgirl

    aquariusgirl Senior Member

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    Ok, I know this may sound a bit out of left field, but the OCD/anxiety thing makes me think about BH4. Genetic inability to synthesise BH4,, interferes with B12 transport & messes with dopamine and serotonin. Low serotonin, cos of low Bh4, leads to loss of gut motility etc.

    Stress depletes BH4 massively from what I read.

    Researchers are talking about BH4 in relation to bipolar and schizophrenia but perhaps milder BH4 deficiency results in anxiety and OCD?

    I notice Dr Amy Yasko is all about lithium these days...and there is a relationship between lithium and BH4. I'm not sure but I think lithium up regulates BH4 genes?

    It would be interesting to know who has got snps in bh4 synthesising and processing genes on their 23andme panels.
     
    kakrpa, Ben H and sianrecovery like this.
  3. kakrpa

    kakrpa

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    I would love to know the answer to this as well - I have mutations that all point to low tetrahydrofolate and am looking into supplementing directly with BH4. My symptoms are severe anxiety/OCD. BH4 may not be a cure, but possibly will help with any underlying BH4 process issue?
     

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