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(Further) Simplified Methylation Protocol Please

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by richard86, Nov 3, 2013.

  1. richard86

    richard86

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    I'm a tad confused by what the actual methylation protocol entails taking. I have been taking 200mcg of Folate as Metafolin (Solgar) daily along with a sublingual Methylcobalamin B12 1000mcg (also Solgar) along with 250mg of L-Glutathione & 100mg of Phosphatidylserine once at night. I usually take CoQ10 too but am all out at the moment. I've been doing this for about 3 weeks now but I was wondering whether I need to be taking anything else & if so where can I get it from (the site the Dr behind the protocol recommends has the supplements he proposes but I can't really differentiate some of them from the ones I'm currently taking & don't want to exceed what is advised)? Preferably I want to get all my supplement from iHerb as that's where I usually shop for them. Also, am I meant to be increasing the dosage if I'm handling it okay & how do I do that (Metafolin 400mcg with 2000mcg of methylcobalamin?). Any tips/recommendations would be immensely appreciated! Thank you.
     
  2. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    Hi,

    What you are taking now is a bit different from what Rich recommended in the Simplified Protocol. Do you have access to his articles and the supplements and doses that he recommends? Rich recommended hydroxocobalamin rather than methyl and some other supplements that you are not taking. Also, he only recommended taking glutathione in special cases. Some of the supplements he recommended are not available at Iherb I'm afraid.

    http://forums.phoenixrising.me/inde...ation-protocol-august-25-2012-revision.19050/

    Also note that the doses Rich suggests are target doses, not beginning doses.

    Best wishes,
    Sushi
     
    helen1 likes this.
  3. richard86

    richard86

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    Hi Sushi,

    Thanks for getting back to me. I've read all the information regarding it but was put onto the current supplements by my current CFS specialist. I also read that Rich prefers Methylcobalamin for its efficacy over Hydroxocobalamin however some patients responded adversely to it & thus he put forward Hydrox... in his protocol as the safer go-to. I don't seem to be reacting to it badly so it seems safe to continue on it. I am completely baffled by the disparity between the Folinic acid & Fola Pro he recommends versus what I'm currently taking (metafolin) & ideally would like to continue taking these supplements or finds ones that mirror the aforementioned on iHerb.

    Cheers!
     
  4. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    @richard86

    If you are happy with your doctor then why not just follow his protocol? There are many ideas about how to treat methylation blocks. But when you mention Simplified Methylation Protocol, that refers specifically to the one outlined by Rich. Maybe that is the confusion?

    Best,
    Sushi
     
  5. Freddd

    Freddd Senior Member

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    Hi Richard,

    I would expect that if you got the Enzymatic Therapy B12 infusion and held it under your lip for 45-120 minutes and 1/4 or so of a Anabol Naturals Dibencoplex between the lower lip and gum and hold for 2 hours you may find things really start up healing then. The folate effective for most everybody is L-methylfolate. I've only tested on myself Metafolin by brand name marketed by Solgar. The 800mcg is only a doller more than the 400mcg and you may need a lot more depending if you develop paradoxical folate insufficiency after things start. However the likely potassium shortage can be dangerous and has landed people in the ER who hadn't come across the warnings or whatever. Have potassium on hand. If you start having sudden intense spasms, writers cramp, legs, whatever, those are some common symptoms of low serum potassium. They often hit the third day after methylation startup along with a need for more potassium. Then everything stops in a different place for each of the next 20 induced deficiencies. That's why I don't believe that any simplified system works. The simplest things is to take at least minimums of the important vitamins and minerals and trace minerals and considerable customization is needed.
     
    helen1 likes this.

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