Marco
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These findings are similar to those previously reported by Lange (if I remember correctly) but this time relates to childhood CFS (CCFS).
Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome
http://www.sciencedirect.com/science/article/pii/S2213158215001618
Some of the authors were also involved in the study that reported on a large 'sensory gating' study in CCFS and the neuroinflammation PET study.
I've only skimmed this so I hope I haven't misparaphrased.
Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome
Patients with CCFS exhibited a wider area of activated frontal regions related to attentional resources in order to increase their poorer task performance with massive mental effort. This is likely to be less efficient and costly in terms of energy requirements. It seems to be related to the pathophysiology of patients with CCFS and to cause a vicious cycle of further increases in fatigue.
http://www.sciencedirect.com/science/article/pii/S2213158215001618
Some of the authors were also involved in the study that reported on a large 'sensory gating' study in CCFS and the neuroinflammation PET study.
I've only skimmed this so I hope I haven't misparaphrased.
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