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Further commentary on the PACE trial: Biased methods and unreliable outcomes

Discussion in 'Latest ME/CFS Research' started by BurnA, Jun 14, 2017.

  1. BurnA

    BurnA Senior Member

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    Abstract
    Geraghty in the year 2016, outlines a range of controversies surrounding publication of results from the PACE trial and discusses a freedom of information case brought by a patient refused access to data from the trial. The PACE authors offer a response, writing ‘Dr Geraghty’s views are based on misunderstandings and misrepresentations of the PACE trial’. This article draws on expert commentaries to further detail the critical methodological failures and biases identified in the PACE trial, which undermine the reliability and credibility of the major findings to emerge from this trial.

    http://journals.sagepub.com/eprint/iXpCNJk6zd34nFpSy4NK/full

     
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  2. JaimeS

    JaimeS Senior Member

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    The Journal of Health Psychology -- if it weren't a conflict of interest, I'd send them a fruit basket. What a breath of fresh air they've been as compared to the intractable Lancet.
     
  3. AndyPR

    AndyPR Tired Sam ate all the cookies!

    Lol, sounds like the start of a film or a book, " @Keith Geraghty , in the year 2016,...", perhaps could have been continued "rode bravely forth, to smite the evil BPS cult, and destroy, once and for all, their deadly weapon, PACE."

    But seriously, thank you Keith for all your efforts. :thumbsup:
     
  4. trishrhymes

    trishrhymes Senior Member

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    Good summing up of most of the arguments. Thank you for all your hard work, @Keith Geraghty.
     
  5. Art Vandelay

    Art Vandelay Senior Member

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    Well done, Keith! Thank you :)
     
  6. Barry53

    Barry53 Senior Member

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    Could always send the Lancet some fruit cakes if you like? :D (English vernacular)

    Edit: Just realised (thanks to google) that in some slang this has derogatory sexual connotations, which is not what I am referring to here.
     
    Last edited: Jun 16, 2017
  7. Barry53

    Barry53 Senior Member

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    I know that this has been hacked to death in the past, but I can't resist.

    ‘too stringent’ - When the PACE authors state this, it begs the obvious question: too stringent for what? Which then begs the obvious answer: Too stringent to get the results they were determined to get. It's like a car being MOT'd and failing because of poor braking efficiency, and then saying the MOT is "too stringent", so modifying the MOT test criterion so it passes! It's such mind bogglingly blatant gamesmanship.

    ‘best evidence’ - is incredibly subjective. The best t*rd in a bucket of sh*t is still a t*rd.
     
  8. Countrygirl

    Countrygirl ME is not MUS

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    Death threat alert! :D

    Couldn't resist this :angel:

    A good idea from China :whistle:

    Anyone like to start a petition to encourage our government to introduce this law into the UK? :lol:


    https://www.statnews.com/2017/06/23...l&utm_source=facebook.com&utm_campaign=buffer

     
  9. TiredSam

    TiredSam The wise nematode hibernates

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    That's an interesting phrase that could do with being introduced in the UK.

    Along with the death penalty for research fraud which leads to harming people, of course.

    Sounds like some of our BPS friends may be safer in Afghanistan after all.
     
  10. Barry53

    Barry53 Senior Member

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    Hmm, China takes it quite seriously then ...
     
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  11. Valentijn

    Valentijn The Diabolic Logic

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    The death penalty is extreme and inhumane, but criminal charges for research fraud that harms patients sounds like a good idea. At the very least, academic fraud and academic dishonesty should have serious career and funding repercussions. But regulatory bodies in the UK don't seem to give a damn, and just keep dishing out the money to the same quacks.
     
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  12. TiredSam

    TiredSam The wise nematode hibernates

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    I've just remembered I'm against the death penalty, so thanks for that reality check. I used to be such a mild chap.
     
  13. Valentijn

    Valentijn The Diabolic Logic

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    It helps to pretend the researchers are extremely stupid or delusional, instead of merely dishonest and unscrupulous about hurting people.
     
  14. Luther Blissett

    Luther Blissett Senior Member

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    Thank you very much @Keith Geraghty for all the work you are doing, along with having to deal with people making your working life 'difficult', it is appreciated and I hope you find some comfort in that fact that it is a deeply ethical and humane project(s).

    A compromise is in the offing, @TiredSam :

    [​IMG]

    In fact they would obviously relish this task while imprisoned, as they do like to stress that 'Work makes you healthy and provides meaning'
     
  15. Barry53

    Barry53 Senior Member

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    I doubt China's motives are so honourable. Probably less about patient safeguards and more about national image.
     
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  16. Valentijn

    Valentijn The Diabolic Logic

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    And another way to get rid of anyone with the wrong enemies.
     
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  17. RogerBlack

    RogerBlack Senior Member

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    Chinese research is (perhaps rightly) getting a _terrible_ reputation.
    Something reasonably needs to be done - is this an appropriate something - probably not.
     
  18. Snowdrop

    Snowdrop Rebel without a biscuit

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    Perhaps it's along the lines of 'weapon's of mass destruction' -- nobody really expects to use them because the results are so extreme the mere threat is deterrent enough.
     
  19. RogerBlack

    RogerBlack Senior Member

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    This will be why the murder rate in US states with the death penalty is so much lower than those without the death penalty. (it's not).

    Rare extreme punishments do not enter into peoples heads when they're doing a thing.
    If policing was such that 50% of study authors with malpractice in were executed, that's of course a rather different thing.
     
  20. Snowdrop

    Snowdrop Rebel without a biscuit

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    You're right. Though my comment was a bit tongue in cheek (really hard to tell I know). Humans are such bold creatures, very little deters us.
     
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