The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Fungus in humans identified for first time as key factor in Crohn's disease

Discussion in 'Other Health News and Research' started by antares4141, Sep 20, 2016.

  1. antares4141

    antares4141 Senior Member

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    Truth or consequences, nm
  2. merylg

    merylg Senior Member

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    Sydney, NSW, Australia
    Interesting! thanks :)
     
    antares4141 likes this.
  3. medfeb

    medfeb Senior Member

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    ditto
     
  4. kangaSue

    kangaSue Senior Member

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    Brisbane, Australia
    The researchers found that;
    [Additionally, test-tube research by the Ghannoum-led team found that the three work together (with the E. coli cells fusing to the fungal cells and S. marcescens forming a bridge connecting the microbes) to produce a biofilm -- a thin, slimy layer of microorganisms found in the body that adheres to, among other sites, a portion of the intestines -- which can prompt inflammation that results in the symptoms of Crohn's disease.]

    Sounds like a case for biofilm disruptors.
     
  5. Forbin

    Forbin Senior Member

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    This seems like a very important finding. It confirms earlier studies about reduced beneficial bacteria in the micorbiomes of Crohn's and chronic ulcerative colitis patients, which is something that was also recently found in Dr. Hanson's study of ME/CFS patients.

    Crohn's study:
    ME/CFS study:
    What might be particularly important is the interplay between various bacteria and (now) fungi involved. It would be remarkable if it turned out that Crohn's, CUC and ME/CFS were manifestations of similar, self-sustaining imbalances, perhaps distinguished by which gut microbes are involved.
     
    Last edited: Sep 21, 2016

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