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Functional impairment in chronic fatigue syndrome, fibromyalgia, and MCS

Discussion in 'Latest ME/CFS Research' started by Frank, Feb 28, 2010.

  1. Frank

    Frank Senior Member

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    Europe
    http://www.cfp.ca/cgi/content/full/56/2/e57

    OBJECTIVE To characterize patients diagnosed with multiple chemical sensitivity (MCS), chronic fatigue syndrome (CFS), or fibromyalgia (FM), to compare their level of function with Canadian population average values, and to assess factors associated with function.

    DESIGN Chart review and abstraction of clinical information.

    SETTING The Environmental Health Clinic (EHC) at Women’s College Hospital in Toronto, Ont, which is a provincial referral centre for patients with illnesses with suspected environmental links, especially MCS, CFS, and FM.

    PARTICIPANTS A total of 128 consecutive patients diagnosed with 1 or more of MCS, CFS, or FM, seen between January 2005 and March 2006 at the EHC.

    MAIN OUTCOME MEASURES Demographic and socioeconomic characteristics, comorbid diagnoses, duration of illness, health services usage, life stresses, helpful therapeutic strategies, and functional impairment measured by the Short Form–36, compared with Canadian population average values. Factors significantly associated with function in bivariate analyses were included in multiple linear and logistic regression models.

    RESULTS The patient population was predominantly female (86.7%), with a mean age of 44.6 years. Seventy-eight patients had discrete diagnoses of 1 of MCS, CFS, or FM, while the remainder had 2 or 3 overlapping diagnoses. Most (68.8%) had stopped work, and on average this had occurred 3 years after symptom onset. On every Short Form–36 subscale, patients had markedly lower functional scores than population average values, more so when they had 2 or 3 of these diagnoses. Having FM, younger age at onset, and lower socioeconomic status were most consistently associated with poor function.

    CONCLUSION Patients seen at the EHC demonstrated marked functional impairment, consistent with their reported difficulties working and caring for their homes and families during what should be their peak productive years. Early comprehensive assessment, medical management, and social and financial support might avoid the deterioration of function associated with prolonged illness. Education and information resources are required for health care professionals and the public, along with further etiologic and prognostic research.
     
  2. shrewsbury

    shrewsbury member

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    This study is out of Canada - a rare thing .

    It used the Canadian criteria for ME/CFS (Carruthers et al, 2003) to define CFS, which is only starting to be used in published
    papers.

    I found parts of it easy to read with light blue boxes and key info bulleted. Here are some of the results:

    [​IMG]

    Figure 1 Comparison of EHC patients and Canadian population averages (women, aged 35 to 54) on the 8 scales of the SF-36

    If the print is too small, the site has an expand button with the chart but I'll link it to here.
     

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