Rich, Thanks for the great info, as always. That is whole realm I had absolutely no knowledge of. Your input is always welcome, IMO. ~~~~~~~ One thing that has helped me in the past (though I haven't taken it in some time due to the multiple protocols currently underway) is an herbal formula called Woman Power from Sarada's Remedies. This is best for regulating erratic cycles, but over time tends to ease much of the PMS symptom picture. Some practical way of addressing the info Rich presented is something I'd like to pursue, as it sounds like it touches the core of the matter. From what I gather from Rich's post, balancing the hormonal picture can only help to a limited degree if the body is predisposed to an inability to break certain hormones down. ~~~~~~~ Finally, a reference for the previous biological descripton I posted, Christanne Northrup describes this same ovulatory phenomenon in Women's Bodies Women's wisdom. It's a thing.