Anyone with cfs/me had improvement after going through all the tests and correcting the different hormones that were out of balance. I tried dhea a few times and get a boost for a short while then nothing really. another doc i see tested me for all the right hormones concerning males, my total testosterone was very good, in the upper 1/4 of range, free testosterone was below the normal reference range, E2 were high and dhea was low, 6 weeks later and after taking 50mg dhea all that happened was my E2 went higher, dhea went higher, free testosterone drop more, mmm confused. I then stopped dhea. So i went back to my cfs doc who immediately put me on arimidex to lower E2 by stopping testosterone aromitizing to E2. I have had blood tests done before arimidex and will have another 6 weeks after starting treatment. My doc seems interested in getting my low dhea levels up as they are good for immune system and are generally low in most people with chronic illnesses. So i take that if my E2 are well controlled by arimidex that he will add dhea, also hopefully arimidex has an effect through lowered E2 on increasing free testosterone and overall hormones become more balance which helps improve health/immune system and i start to look healthier and lose some weight and have the energy to through some weights around again. thoughts and opinions welcome.