Hi Madie, I have everything on-hand, including potassium. I would like to be able to distinguish the benefits of the adb12 from the benefits of mb12, especially since I might only need the adb12 once a week. Does it make any difference which I add first (mb12 or abd12)? Tyipically I would suggest mb12 be started first. The problem is it may take you months to reach mb12 saturation so that you can tell if the adb12 has much of an added difference. Most people top out on adb12 in a couple of doses in a couple of days. Since some of it converts, not much, but some, to mb12 you wll never top out the mb12 on adb12. SOme of the healing won't start until you start adb12 so you don't want to wait months to start it. If a person is going to start adb12 first, I suggest only 1 or 2 days before. Too much adb12 compared to mb12 causes it's own problems. If you just go in gangbustes on mb12, 15mg daily sublingual 45-120 minutes), you could reach saturation in a month or so. After you reach saturation in the body on both, then separate 50mg trials for the CNS deficiency is easy. But it has to be that a person has no reaction at 15mg and that 20 causes no change. With the adb12 10mg a day until there is no body response that can be felt, usually after day 3 or so is fine. Then when the body is saturated with both, try 50mg single sustained dose of mb12 sublingual. Body response has to be gone because CNS response is too subtle to feel otherwise. Then next day try 50mg ADB12. Same as the mb12, if any body reponse left then overwhelm brain. If you have a separate adb12 reponse in the brain, you would have in the body as well. It is important to know if there is a separate CNS response to either or both so you can plan accordingly. If I choose to start with lower doses (quarter or half tablet), how long should I wait before increasing? That depends upon what stories you tell yourself about the startup effects. Please understand that many docs would just start you on 1mg injection, about the same as a 5mg sublingual held for 45-120 minutes. While dose proportionate the response is not linear. A half a tablet can allow startup to go on for months and months. At 15mg a day, as 3 doses of 5mg, in a month or so, startup will likely be complete. It will be somewhat stronger than 1mg. You probably want to hold level until you get potassium under control and see what other induced deficiencies show up. Then as you increase continue watching.