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Folate Issues & Methylation

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by madietodd, Jan 24, 2012.

  1. Gavman

    Gavman Senior Member

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    Sydney
    Diarrhoea, here we go again (sung to Abbas Mama mia)
    With diarrhoea, dry foods are important to help keep down food. I have vegemite toast, water, electrolyte drinks and I afford myself the luxury of doing nothing but sleeping and maybe reading. Things to promote the slowing of the digestion.
    Avoid creamy foods, milk, sugars, overly hot or cold foods, sauces, high processed foods. And have an electrolyte drink on hand. - Make sure its one you are ok with (id avoid ones with maltodextrin (corn syrup and high contents of processed sugars) - chemists generally have decent ones.
    The plainer the better so your stomach can settle.
  2. madietodd

    madietodd Senior Member

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    East Coast, USA
    Thanks, Gavman. I looked up diarrhea yesterday, and some govt agency has a simple formula: water + salt + sugar, and I'm drinking that. One advantage to waking up every hour all night long is that I drank a liter of this during the night.

    I called a nurse last night, and she said carbs - makes sense. So I choked down some rice, and I'll manage some oatmeal this morning. I haven't been able to eat anything 'fancy' - it's been bits of egg, fish, and broccoli and some gluten-free crackers or toast. I'm already off dairy - the nurse asked about that too.

    I ate a few strawberries yesterday afternoon, and I think that's what set off a 5-hour disaster. So yeah, dry toast, rice, oatmeal.
  3. Freddd

    Freddd Senior Member

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    Salt Lake City
    HI Madie,

    Do you have any other flaring symrtpoms with the diarhea that mighrt indicate low folate? Here are the symtpoms again.


    Group 1 – Hypokalemia onset. Symptoms may appear with serum potassium as high as 4.3. May become dangerous if ignored. Considered “rare” with cyanocobalamin it is very common with methylb12 and adensosylb12 and less so with hydroxycobalamin..

    IBS – Steady constipation , Nausea, Vomiting, Paralyzed Ileum, Hard knots of muscle, Sudden muscle spasms when relaxed, Sudden muscle spasms when stretching , Sudden muscle spasms when kneeling, Sudden muscle spasms when reaching , Sudden muscle spasms when turning upper body to side, Tightening of muscles, neck muscles, Muscle weakness, Abnormal heart rhythms (dysrhythmias), Increased pulse rate, Increased blood pressure, Emotional changes and/or instability, dermal or sub-dermal Itching, and if not treated potentially paralysis and death.



    Group 2a - Both

    IBS – Diarrhea alternating with constipation, IBS – Normal alternating with constipation



    Group 2b – Either or both

    Headache, Increased malaise, Fatigue



    Group 3 - Induced and/or Paradoxical Folate deficiency or insufficiency

    IBS – Steady diarrhea, IBS – Diarrhea alternating with normal, Stomach ache, Uneasy digestive tract, increased hypersensitive responses , Skin rashes, Increased acne, Skin peeling around fingernails, Skin cracking and peeling at fingertips, Angular Cheilitis, Canker sores, Coated tongue, Runny nose, Increased allergies, Increased Multiple Chemical Sensitivities, Increased asthma, Generalized inflammation in body, Increased Inflammation pain in muscles, Increased Inflammation pain in joints, Achy muscles, Flu like symptoms, Depression, Less sociable, Impaired planning and logic, Brain fog, Low energy, Light headedness, Sluggishness, Forgetfulness, Confusion, Difficulty walking, Behavioral disorders, Dementia, Reduced sense of taste, Increase irritability, Loss of reflexes, Fevers, Old symptoms returning, Heart palpitations, Bleeding easily.



    Group 4

    Itchy bumps generally on scalp or face that develops to acne like lesions in a few days from start.



    Group 3 symptoms, induced paradoxical folate deficiency or insufficiency are corrected quickly with titrated doses of Metafolin, methylb12 and adenosylb12. If glutathione (precursors) are the cause then larger doses of Metafolin, 7.5-15mg,or maybe more are needed. Different tissues are affected at different levels of methylfolate, it comes or goes in stages. Very strong dose proportionate characteristics are present. Serum folate levels may be high or even very high despite Metafolin responsive deficiency/insufficiency symptoms.

    Group 1 symptoms respond readily to potassium. The symptoms and response to potassium may occur at a serum level of 4.3 or less.
  4. madietodd

    madietodd Senior Member

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    East Coast, USA
    Hi, Freddd,

    No, I haven't had any other symptoms. At the beginning I had awful intestinal pain, but only the first 2 days or so. Then some days I would have 'normal' energy and go out running errands, and some days I'd read all day on the couch. No fever, rashes, etc. Two days involved particularly long hours in the bathroom, and of course these wrung me out.

    I started seriously rehydrating 2 nights ago, and promptly got an extraordinarily stiff neck and spine + headache. One member says that happens when we rehydrate.

    Yesterday's diet of oatmeal, rice, and three liters of rehydration fluid has worked.

    I am sufficiently spooked by this that I have made an appointment with Nancy Klimas' people, in August.

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