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fMRI bugs may invalidate many scientific papers

Discussion in 'Other Health News and Research' started by user9876, Jul 5, 2016.

  1. user9876

    user9876 Senior Member

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    It appears that there may be bugs in the statistical software used to derive results from fMRI scans

    Paper:
    http://www.pnas.org/content/early/2016/06/27/1602413113.full

    News article
    http://www.theregister.co.uk/2016/0...uld_upend_years_of_research/?mt=1467666616578
     
    aaron_c, MeSci, taniaaust1 and 3 others like this.
  2. aimossy

    aimossy Senior Member

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    woah........
     
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  3. Woolie

    Woolie Senior Member

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    Interesting article, @user9876. Its about resting state fMRI, which is where you measure blood oxygen uptake patterns when a person is "at rest" (lying in darkness). They found one particular type of analysis - clusterwise analysis - didn't correct very well fro multiple comparisons.

    So this means that we should be cautious about studies reporting group differences on resting state fMRI when the study uses clusterwise analysis. Otherwise, its business as usual.
     
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  4. Effi

    Effi Senior Member

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    Europe
    MEMum, Valentijn and MeSci like this.

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