Hmm, thanks Tania. Turns out my doc wants me to try the saline w/out the florinef first anyway. I WAS wondering about how long the saline would last. I had my first saline iv Mon. p.m. and felt better Tues. though... my pots was so bad last night (Tues. p.m.) that I had to sleep with the compression socks on. I need to find out how often to have the saline iv's I guess. Any ideas? I can't see driving 45 min.'s to the doc. for a saline drip every few days for the rest of my life. Though... I would do it if it as long as I could if it made me better. I heard recently from someone who said getting her cortisol levels straightened out the POTS/OI. She followed "Adrenal Fatigue" by James Wilson. I'm going to try it. Again. What the heck. The nurse where I get iv's/hbot said her son had the OI issues when he was really thin and gaining weight helped. I'm thin but it's not an idea I'd like to pursue.