1. Patients launch a $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Part 2: Brain Cells Making us Sick? Messed up microglia could be driving symptoms
Simon McGrath looks at theories that microglia, the brain's immune cells, might be overactive and driving the symptoms of ME/CFS and fibromyalgia.
Discuss the article on the Forums.

Florinef and High BP.

Discussion in 'Problems Standing: Orthostatic Intolerance; POTS' started by Ema, Nov 19, 2013.

  1. Ema

    Ema Senior Member

    Messages:
    3,142
    Likes:
    3,238
    Midwest USA
    I've been struggling again with my OI and I'm debating going back onto Florinef. It worked really well for me in the past but that was at a time when my BP (especially diastolic) was quite low.

    Now I'm at a place where my BP is good to high (usually 120-130/80s), my aldosterone levels are optimal, and my sodium is OK (could be a little higher). But I'm dizzy!

    Has anyone taken Florinef with normal BP? Does it raise it excessively?

    Does Florinef work to expand the blood volume if the blood volume and pressure already appear normal (based on BP and electrolytes)?

    I'm fine to take Florinef again but I just don't want to do it if it is going to cause more problems than it solves this time around. If my diastolic BP was still in the 50/60s, I would do it in a heartbeat though.

    Any thoughts?
  2. taniaaust1

    taniaaust1 Senior Member

    Messages:
    7,719
    Likes:
    4,561
    Sth Australia
    Lots of people take florinef with normal BP just due to having POTS and is the most common POTS treatment (that is enough without having any aldosterone issues going on too for most POTS doctors to prescribe it.. many POTS people dont have BP issues too).

    Yes it does

    Im taking Florinef with high BP as what sends my BP very high is hyperPOTS (orthostatic hypertension) which can also be connected to having low blood volume. In this case it can be useful thou normally contraindicated in high BP people.

    Dr David Bell gets the blood volume up to bring down the BP of the orthostatic hypertension with low blood volume group when he gives them saline IV to bring down the hypertension (which must work or otherwise he wouldnt talk of doing that)

    So anyway, the normal rules can be very different in us with things actually having the opposite affect due to the different issues we have and quite possibly in me, the florinef helps my high BP.
    Ema likes this.
  3. SOC

    SOC Moderator and Senior Member

    Messages:
    5,139
    Likes:
    5,950
    USA
    I had normal to borderline high BP (the same as yours) when I started Florinef (and verapamil for tachy). My BP not only did not climb, it actually has dropped to consistently normal or normal low. I feel much better with increased blood volume.
  4. Ema

    Ema Senior Member

    Messages:
    3,142
    Likes:
    3,238
    Midwest USA
    @taniaaust1 , @SOC , thanks for the replies. That makes me feel much better.

    How much do you all take?
  5. SOC

    SOC Moderator and Senior Member

    Messages:
    5,139
    Likes:
    5,950
    USA
    I take 0.25 mg which is a little on the high side. Daughter takes 0.1 mg, which is more common iirc.

    Oh, and I take it in split doses --0.2 in the morning and 0.05 midday.
  6. ggingues

    ggingues $10 gift code at iHerb GAS343 of $40

    Messages:
    3,914
    Likes:
    782
    Concord, NH
    By split you mean 2 different doses, right? My Dr recently started me on 0.05 mg and kicked it up to 0.1 mg in the morning.

    GG
  7. SOC

    SOC Moderator and Senior Member

    Messages:
    5,139
    Likes:
    5,950
    USA
    Yes, 2 different amounts at 2 different times. I take 0.2 mg first thing in the morning and then a "booster" of 0.05mg midday.
    ggingues likes this.
  8. xks201

    xks201 Senior Member

    Messages:
    606
    Likes:
    178
    so your dizziness is gone after remaining on florinef at .25mg? How long did it take for the high BP reaction to go away from it? Were your sodium levels normal before taking it too?
  9. Lilly1212

    Lilly1212

    Messages:
    7
    Likes:
    0
    Now up to a full tab of florinef and two 20meq tabs if slow release potassium ..... I'm trying to drink more sea salt water, but 3 teaspoons a day is leaving me more dry mouthed than anything .... My blood pressure gets better when standing with the higher salt intake but I'm not feeling right at three teaspoons a day.... Sodium is stuck at 140... Not budging.....do you think I may end up needing more than one tab a day of florinef???? Before starting my aldosterone was a 2...... I'm so confused and not feeling well....taking 25mgs of HC and 3 NDT a day.....all i want to do is heal my adrenals so I can optimize my thyroid!!!! Any input would be appreciated.....
  10. Lilly1212

    Lilly1212

    Messages:
    7
    Likes:
    0
    Does increasing salt intake in florinef waste potassium further? I'm a mess today.... Sick to my stomach, panicky , awful. Any help would be appreciated !!!!
  11. heapsreal

    heapsreal iherb 10% discount code OPA989,

    Messages:
    7,066
    Likes:
    4,280
    australia (brisbane)
    what about trying the rehydration type drinks etc, as they generally have a few more electrolytes then just sodium that may help??
    ggingues likes this.
  12. xks201

    xks201 Senior Member

    Messages:
    606
    Likes:
    178
    Florinef at even half a pill a day jacks up my blood pressure. I feel like I constantly need more sodium though based on my symptoms - yet I can't handle more Florinef. Increasing my fluid volume with desmopressin somewhat helps, but probably not enough to be able to tolerate more florinef.
  13. Ema

    Ema Senior Member

    Messages:
    3,142
    Likes:
    3,238
    Midwest USA
    Do you have adrenal insufficiency as well?

    What is your BP now?

    Where is your potassium on labs with 1 tab of Florinef and 40 mEQ of KDur?

See more popular forum discussions.

Share This Page