I read an interesting comment on a thread yesterday where a member said that they believed the cure/solution to ME would probably come from someone we don't expect...a cancer researcher. That got me thinking, in Cort's most recent article one of the researchers said that ME is most similar to cancer from a mitochondrial standpoint. I decided to do a bit of searching and came across this... Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells Looks kinda familiar right? I wonder if there has already been a lot of work done out there that can help us solve ME faster. This also gave me quite a bit of hope.