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Fixing Leaky Gut Helps ME/CFS, and Sometimes Achieves Full Remission

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by Hip, Nov 29, 2011.

  1. mermaid

    mermaid Senior Member

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    Well, yes, I did have acid reflux, but no longer have it since I started on the Betaine, though I can't say that's the only reason, and it almost certainly isn't the only reason. To be honest I didn't have a lot of reflux exactly, unless I ate certain foods, but as Dr Myhill felt that I had hypochlorhydria I went with that along with the other things I changed.

    Having read Dr M and others on this acid issue, standard medical practice IS to treat with alkali (well they treat often with PPIs - and I assume they are alkali?), but my understanding is that the SYMPTOMS for low acid and high acid are the same (ie acid reflux). I always treated it cautiously as I knew I had a tendency towards gastritis and I certainly didn't want to worsen that, but in the end it seemed to work.

    I have tried stopping it in the past to test whether all was well now, and at the time it wasn't, but it might be worth me easing off it a bit now, and hope that my own acid production is up to scratch again.

    And yes, if you are vegan, maybe you wouldn't have such problems, as I believe that more acid is needed for higher protein meals.
    aimossy and justy like this.
  2. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    PPIs reduce acid so have an alkalising effect. HCl and PPIs have opposite effects, and PPIs can actually cause hypochlorhydria.

    I'm by no means an authority on hypochlorhydria but have found a few references to the symptoms being similar to excess acidity, but not sure whether there is actual acid reflux in hypochlorhydria - it seems counter-intuitive.
    aimossy and mermaid like this.
  3. pattymelt

    pattymelt

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  4. Hip

    Hip Senior Member

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    @pattymelt
    I took these on an empty stomach, with a large glass of water.

    The supplements N-acetyl-glucosamine, zinc, zinc carnosine and glutamine are certainly best taken on an empty stomach; for the other supplements, it is not so important when you take them.
  5. dannybex

    dannybex Senior Member

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    Do you know if carnosine taken by itself chelate or bind to zinc or other minerals?
  6. Hip

    Hip Senior Member

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    No, I don't believe it does. Zinc carnosine supplements are not just zinc and carnosine together in a capsule or tablet.

    Zinc carnosine is in fact a zinc molecule chemically bonded to a carnosine molecule. The combination of the two becomes in effect a new chemical molecule. This way of loosely bonding of two different molecules together is called a molecular complex.

    A molecular complex is defined as two or more molecules loosely bonded or "glued" together. This bonding between the molecular components of a molecular complex is normally weaker than the normal covalent bonds found in much of chemistry.

    The Meriva® curcumin supplement, which is more absorbable that regular curcumin, is another example of a molecular complex. In this case, a curcumin molecule is bonded or "glued" to a phosphatidylcholine molecule.
    end and dannybex like this.
  7. Leopardtail

    Leopardtail Senior Member

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    My pet love is smoked almonds :)
  8. Xhale19991

    Xhale19991

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    What type of diet do you recommend to heal leaky gut?
  9. Hip

    Hip Senior Member

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    A low lectin diet, which avoids the food groups: beans, nightshades and grains, which can worsen leaky gut.

    If you cannot fully avoid these food groups, then taking some sugar with them appears to lessen their bad effects — see this study.
  10. Xhale19991

    Xhale19991

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    So basically a paleo diet?

    Do you advocate ketosis? Or just low carb but not low enough to bring about that state?
  11. Hip

    Hip Senior Member

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    @Xhale19991
    I have never seen any evidence for ketogenic diets helping leaky gut.

    Supplements proven to reduce leaky gut (ie, backed up by published studies) are given in the first post of this thread. I'd suggest taking a set of those supplements if you want to try to combat leaky gut.
    end likes this.
  12. Xhale19991

    Xhale19991

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    Then what source of carbs can you consume safely? Without grains, legumes, or nightshades..... what else is left? I also heard fruit was bad for those with gut issues.
  13. Hip

    Hip Senior Member

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    @Xhale19991
    I personally only avoid gluten containing grains, but eat all other grains. And I also eat potatoes. So this gives me quite a range of carbs to eat. But I avoid all beans, and all nightshades other than potatoes.
  14. dmholmes

    dmholmes Senior Member

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    White rice, potatoes, sweet potatoes, taro, carrots, jicama...
  15. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    I've cut down on sweet potatoes, which I had recently experimented with as a replacement for potatoes, but this coincided with a worsening of symptoms, and I found it too strong-tasting to use as a 'canvas' for stronger flavours. It also tasted too sweet for me. I'm back to good ol' spuds. I was OK with them before, but something had worsened my symptoms even before the sweet potato, and I think I was eating too many nuts. Bowel function is much better after reducing my intake to what it was before.

    Maybe amaranth is suitable. I've tried rolls made from this and it was OK (but expensive). Quinoa seems OK too but to me very bland.
    aimossy likes this.
  16. tinek

    tinek

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    Pumpkins: butternut squash roasted, spaghetti squash, cabbage, beets, carrots, cauliflower, broccoli, greens like spinach. Pick up a good paleo cookbook and go exploring or like ThePaleoMom on Facebook to get a steady stream of paleo recipes :)
    Paleo does not have to be low in carbs, but it has to be low in irritants. They make it low carb for weight loss.
    I'm myself starting a protocol per the new The Paleo Aproach book to get my digestive issues resolved, everything else is much better since starting regular paleo.
    dmholmes likes this.
  17. end

    end Senior Member

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    I think Hip has a point... I went ketogenic for ages and it acterly made me feel more toxic/fatigued. And follow up IP testing was made even worse.

    I think the avoidance of grains/nightshades still holds some merritt though
  18. end

    end Senior Member

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    Fruit is high in fructose and with a lot of us being sensitive to it along with lactose as per KDM's finding's would indicate we should probly avoid both....
  19. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Hip likes this.
  20. Leopardtail

    Leopardtail Senior Member

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    @MeSci

    I remember seeing a study some time ago in which KDM experimented with a cocktail of supplements including 5-MTHF to restoring the digestive tract. Does it ring any bells will you? I have been having trouble re-locating it.

    B.

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