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Fingernail problems

Discussion in 'Skeleton, Skin, Muscles, Hair, Teeth, and Nails' started by Ocean, Dec 10, 2011.

  1. Ocean

    Ocean Senior Member

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    I have horizontal ridges on one of my fingernails and little pitted indentations on others. Here are some pictures from google that resemble what I have:

    pitted nails

    Beau's lines

    I plan to ask my doctor about this. The internet says it could be a sign of disease or nutritional deficiency.

    I was just wondering if anyone else had either of these two issues and if you did if you found out what it was from and if it got fixed somehow.

    Thank you!
  2. Dreambirdie

    Dreambirdie work in progress

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    There are probably a number of deficiencies that can cause fingernails to become ridged and pitted.

    I had very fragile fingernails, which chipped and peeled easily. What helped me was biotin, which is a B vitamin.
  3. Ocean

    Ocean Senior Member

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    Thanks Dreambirdie.
  4. Annesse

    Annesse Senior Member

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  5. Ocean

    Ocean Senior Member

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    Thanks Annesse, Last time I had it checked my levels were normal. But the nail thing is pretty recent so I'll ask my doctor to check next time, my levels might have dropped in the past few months for some reason. Thank you!
  6. richvank

    richvank Senior Member

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    Hi, Ocean.

    Nails and hair are made of alpha keratin proteins. They get their strength from crosslinking between adjacent protein molecules by disulfide bonds between cysteine residues in the proteins. I think that the reason nails and hair become weak or brittle in ME/CFS is that cysteine becomes deficient. This occurs because of the disruption of the sulfur metabolism caused by the vicious circle mechanism that includes a partial block in methionine synthase. To tie in with what Annesse wrote, part of this vicious circle mechanism in ME/CFS is a functional deficiency in vitamin B12, which is caused by glutathione depletion, also part of this vicious circle mechanism. Note that in ME/CFS, there is usually a functional deficiency in vitamin B12, rather than an absolute deficiency. Measurement of the blood serum B12 level is often within or even above the normal range, but the cells are not able to use it effectively, so it continues to be recirculated between the blood, the liver, and the gut.

    Lifting the partial block in the methylation cycle by means of one of the methylation protocols should correct problems with the nails and the hair.

    Best regards,

    Rich
  7. Ocean

    Ocean Senior Member

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    Thank you Rich. Do you think if you have a chance you could look at my post about supplements? I'm very reluctant to try more supplements because I always have so much trouble with them and from what I read the methylation protocol relies on supplements? I haven't felt great after taking sublingual methylB12 either. I just wondered if you have any thoughts on trying it despite my usual issues with supplements. The post is here:
    http://forums.phoenixrising.me/showthread.php?15157-Problem-with-supplements-especially-vitamin-D
    If you have a chance to look at it I'd appreciate it a lot. Thank you!
  8. Jenny

    Jenny Senior Member

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  9. uni

    uni

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    Hi,

    I've definately noticed my nail quality getting worse after getting CFS. I'm guessing its either due to nutritional deficiencies, oxidative stress, or the methylation issue that Rich talks about.

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