Really just here to discuss and hopefully help someone else down the road. I've struggled to dial in my methylfolate dose almost as much as I did getting my mB12 dose dialed in. I've put a solid month and a half into experimenting and I've begun noticing patterns. As I suspected earlier, they don't really follow the patterns most others experience. Which is why I hope this will someday help another person like me. 0mg mFolate - before I started it, I noticed that I was WAY over energized on just mB12, and burning out by 4pm every day. Super excited, constantly euphoric. 1mg mFolate - still too low, and way over excited. So euphoric it hurts. I meditate daily, and I can feel energy during my practice flowing through me. Sounds awesome right? Except in the evening, I'm crashing. And struggling to not blurt out obnoxious things just because I feel so damn awesome. It's a dangerous spot to be in, IMO. Insomnia is also prevalent. I have a fair amount of experience at this dose. 2mg mFolate - this is where things seem to start getting under control for me. I still feel very "electric" and full of energy, with a great mood overall, but not so much that it's distracting. I can begin to focus on things again. For me, this has become the lowest dose I feel comfortable at. 6mg mFolate - I stayed at this dose for a long time (several months) without thinking twice about it. It wasn't until I went back down to 2mg that I realized 6mg was too sedating. I felt very calm and collected, but I was tiring out way too easily. 15mg mFolate - I feel so calm at this dose it's ridiculous. Thing is, I'm so sedated I can barely get anything done. Easy to fall asleep. I think somewhere between 2mg and 6mg is going to be my target dose now. I've been on 1mg all this week (3rd test at this dose I think), and I can't even sit still. It's so much that it takes me beyond being energized and outgoing - my mind is racing so fast I can't even formulate sentences without really trying. It's crazy. Anyways, hope this pops up on Google for someone like me someday. Cheers!