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Fibromyalgia solved; a pathology not in the mind (research)

Discussion in 'Fibromyalgia' started by Kina, Oct 19, 2013.

  1. Marco

    Marco Old blackguard

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    Near Cognac, France
    http://psychcentral.com/news/2013/0...-biological-basis-for-fibromyalgia/56233.html

    I'm not so sure about specific or diagnostic of fibromyalgia.

    Interestingly the same pattern of peripheral neuropathy and AV shunt dysfunction is found in type II diabetes and leads to similar thermoregulatory problems :

    http://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2008.02395.x/abstract

    Likewise in 'complex regional pain syndrome' :

    http://www.rsds.org/pdfsall/Systemic-Complications-of-CRPS.pdf
    WillowJ, Emootje and Esther12 like this.
  2. Marco

    Marco Old blackguard

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    Near Cognac, France
    More on complex regional pain syndrome :

    Bold added!

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661922/
    WillowJ and Esther12 like this.
  3. Esther12

    Esther12 Senior Member

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    Thanks Marco. Unless we understands the specifics, it's worth being wary of what could be the hyping of results.
    Shell likes this.
  4. Marlène

    Marlène Senior Member

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    Edegem, Belgium
    I always had "winter hands" as a teenager. They hurt soooo much. Ten years later I developed a glomus tumor in my thumb. It took them another 10 years to find out what was causing the excrutiating pain.
    "Glomus tumors are thought to arise from the glomus body, a thermoregulatory shunt concentrated in the fingers and toes."
  5. AbbyDear

    AbbyDear

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    Wow, that's encouraging to hear of published article favoring physiological pathology contradicting a psychosomatic infuence.

    I am a bit skeptical (maybe concerned is a better word) that big pharma is involved.

    While they seemed to stress that it may be a nerve problem (feedback), but maybe there is a metobolic/mitachondria effect on temperature regulation as well. I can imagine CNS issues can paly a part.

    I do not have FM type issues, but I do have a lot of pain. I also have circulation issues, with relatively low blood pressure. I have often thought about capillary not functioning properly, e.g. large (possibly immune) cells getting in the way (or large protiens, toxins making it through leaky gut), or red blood cells too large or not flexible enough, or simply the capillaries not flexible enough. But I have also thought that maybe the feedback (nerves) may be messed up. One thought there was that maybe the brain senses circulation issues and attempts to 'relax' the arteries - resulting in low blood pressure... but the capillaries are still under functioning, having challenge.

    One thing I can attest to - poor circualtion is itself a positive feedback mechanism - in that once tissue damage occurs (becomes hard, less flexible), circulation, especially at the capillary level becomes even worse, thus leading to more tissue damage, thus leading to poorer circualtion, etc. I can imagine heart attack issues to be a prime example, but I do not think most docs get this, or the seriousness/urgency of poor circulation (chronic). I get the feeling they believe you can only get peripheral circulation problems as a result of diabetes (only).
  6. SilverbladeTE

    SilverbladeTE Senior Member

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    Somewhere near Glasgow, Scotland
    [​IMG]


    Revenge is a dish best served cold, with law suits and journals retracting pishbag studies by psychiatrist SONS OF BITCHES! :thumbsup:
  7. vamah

    vamah Senior Member

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    Washington , DC area
    Fire and blood!
    SilverbladeTE likes this.
  8. Snowdrop

    Snowdrop Senior Member

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    Toronto
    Yup. You can't put enough arrows in the (hopefully) now antiquated old paradigm. :grin:
    SilverbladeTE likes this.
  9. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    Midwest, USA
    At home, I wear a light pair of sock, a heavy pair of socks, and those hospital slipper-socks with the treads on the bottom. The slipper-socks are some my Dad got when he was in the hospital, so they are 'too big' for me, but just right over a couple of pairs of socks.
  10. rosie26

    rosie26 Senior Member

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    Warm your feet in some warm - hot water before putting your socks on. I find this helps to keep them warm and doesn't take forever for feet to warm up in socks. x
  11. barbc56

    barbc56 Senior Member

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    This is interesting but not sure what it means as I don't completely get the science. Looks like this artical might be a bit of journalistic hyperbole as other conditions have this? Possibly the chicken/egg issue? Still interesting though.

    http://edsinfo.wordpress.com/2013/10/20/headline-fibromyalgia-solved/

    Sorry for not being able to make the linky one click. I want my laptop back but may not get it for a few more days!

    Edit. Well for heaven's sake, the url worked! Maybe the spellcheck will start working? It's still too hard for me to type on my tablet. Ugh!
    Esther12 likes this.
  12. Esther12

    Esther12 Senior Member

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    Ta barb. It's important to realise how much spin there is in science, and not allow oneself to accept the headlines one wants to be true, while only be sceptical, cautious and critical of the other stuff.

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