....for about the past couple of months, nearly every afternoon at about 4 or 5 pm, I start to feel very cold. Once I put on extra warm clothing/socks/footwear I'm usually ok and then sometimes just a few hours later I feel normal again. It is summertime at present so the weather is not cold. I was reflecting on this phenomena this afternoon and it is about six months - give or take, since I commenced Beta Blockers but other than that, nothing else really has changed. Any possible connections to M.E. or meds?