In the past two months I have had 2 stubborn sinus infections. Each time I was given antibiotics and Prednisone (8 day pack). Each time I was on the Prednisone, I felt better not only with my sinuses but with my other symptoms as well. When I went off the pPednisone, I felt lousy. (worse then when I started). This happened both times that I took the Prednisone. Since steroids treat inflammations and I know I have a symptoms of inflammation in my body, wouldn't it make sense to treat my ME/CFS with steroids? My C-reactive protein is high (7). I have very high tithers to many viruses in my blood work. I am positive for mycoplasma. Did anyone have a similar experience with Steroids? Is anyone on steroids now and is being helped by it?