1. Patients launch a $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
New Exercise Study Brings Both Illumination and Questions
Simon McGrath looks at new objective evidence of abnormal response to exercise in ME/CFS patients, and the questions that researchers are still trying to answer ...
Discuss the article on the Forums.

Fed up of waking up every night at 3 am

Discussion in 'Sleep' started by Marlène, Oct 12, 2013.

  1. Valentijn

    Valentijn Activity Level: 3

    Messages:
    5,869
    Likes:
    7,939
    Amersfoort, Netherlands
    I don't get hypotension from NAC, and not sure if it's even possible for it to cause hypotension (it's just an amino acid).
  2. MeSci

    MeSci ME/CFS since 1995; activity level 6

    Messages:
    3,017
    Likes:
    3,364
    Cornwall, UK
    Try asking in this forum.
  3. Sing

    Sing Senior Member

    Messages:
    1,301
    Likes:
    421
    New England
    Thanks for telling me about your experience. It could be that my increased problem with hypotension right now has been caused by the long-running respiratory infection I have had. I laid off NAC for a few nights so far and nothing has changed with the worsened hypotension. Maybe when I am over this infection and well into recovery, my OI will go back to par.
  4. MeSci

    MeSci ME/CFS since 1995; activity level 6

    Messages:
    3,017
    Likes:
    3,364
    Cornwall, UK
    I'm surprised that you say this. Amino acids are powerful chemical compounds. I did a quick Highwire search and found lots of scientific papers describing effects from NAC, including this one which refers to it reducing blood pressure when administered along with arginine.
  5. Sing

    Sing Senior Member

    Messages:
    1,301
    Likes:
    421
    New England
    Looking up NAC and nitric oxide and hypotension, I found a similar paper but on the effect with rats. Heart rate and blood pressure went down with NAC, due to the increase of NO, nitric oxide, was the jist I got.

    But, if you don't have hypotensive problems, but are normal or hypertensive, NAC might be a safe help as well as a good one. Just my opinion.
    MeSci likes this.
  6. MeSci

    MeSci ME/CFS since 1995; activity level 6

    Messages:
    3,017
    Likes:
    3,364
    Cornwall, UK
    I am thinking of taking this myself, not due to sleep problems but for current low mood, so have tried to find some more info. There is a good page here, which is on a site that looks very rigorous, thorough and impartial.
  7. Marlène

    Marlène Senior Member

    Messages:
    441
    Likes:
    210
    Edegem, Belgium
    I got a tip and it works (sometimes):

    drink a glass of orangejuice + 3 grains of himalayan salt just before bedtime.

    The sugar is to feed the liver and the salt the adrenals at night. That way you won't (easily) wake up from the adrenaline rush.

See more popular forum discussions.

Share This Page