New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
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Fed up of waking up every night at 3 am

Discussion in 'Sleep' started by Marlène, Oct 12, 2013.

  1. Valentijn

    Valentijn Activity Level: 3

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    Amersfoort, Netherlands
    I don't get hypotension from NAC, and not sure if it's even possible for it to cause hypotension (it's just an amino acid).
     
  2. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    Try asking in this forum.
     
  3. Sing

    Sing Senior Member

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    Thanks for telling me about your experience. It could be that my increased problem with hypotension right now has been caused by the long-running respiratory infection I have had. I laid off NAC for a few nights so far and nothing has changed with the worsened hypotension. Maybe when I am over this infection and well into recovery, my OI will go back to par.
     
  4. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    I'm surprised that you say this. Amino acids are powerful chemical compounds. I did a quick Highwire search and found lots of scientific papers describing effects from NAC, including this one which refers to it reducing blood pressure when administered along with arginine.
     
  5. Sing

    Sing Senior Member

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    Looking up NAC and nitric oxide and hypotension, I found a similar paper but on the effect with rats. Heart rate and blood pressure went down with NAC, due to the increase of NO, nitric oxide, was the jist I got.

    But, if you don't have hypotensive problems, but are normal or hypertensive, NAC might be a safe help as well as a good one. Just my opinion.
     
    MeSci likes this.
  6. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    I am thinking of taking this myself, not due to sleep problems but for current low mood, so have tried to find some more info. There is a good page here, which is on a site that looks very rigorous, thorough and impartial.
     
  7. Marlène

    Marlène Senior Member

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    Edegem, Belgium
    I got a tip and it works (sometimes):

    drink a glass of orangejuice + 3 grains of himalayan salt just before bedtime.

    The sugar is to feed the liver and the salt the adrenals at night. That way you won't (easily) wake up from the adrenaline rush.
     

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