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FDA/NIH PAPER in PRESS, by Mindy Kitei

Discussion in 'Media, Interviews, Blogs, Talks, Events about XMRV' started by Mindy Kitei, Aug 10, 2010.

  1. Robyn

    Robyn *****

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    If they at least say they found positives of a relevant degree. I would be happy with that. I think it could be highly possible they might change some wording in regards to the blood supply to avoid panic.
  2. VillageLife

    VillageLife Senior Member

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    Its a sad day that im this excited about a retrovirus! .......I guess its justice.:Retro smile:
  3. anciendaze

    anciendaze Senior Member

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    Maybe we should add "excessive heartrate response to publication of scientific papers about a retrovirus" to the list of symptoms.
  4. SOC

    SOC Moderator and Senior Member

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    Okay. Sounds entirely fair. :Retro smile: One gets bragging rights, one eats her/his words. If it's debateable (which seems unlikely) we take a vote in the forum as to whether the paper fails your criteria, okay?

    I admit I am inviting cosmic level jinxing, but WTH. :D
  5. SOC

    SOC Moderator and Senior Member

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    LOL!

    Assuming this comes off, it's going to be the lowest key massive celebration in history. Or maybe we will have people leaping from their wheelchairs and dancing in the streets. :D
  6. shrewsbury

    shrewsbury member

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    What do I want to see to celebrate? These points from the Alter presentation slide from the Zagreb blood safety conference

    -----------------------------------------
    Dr. Alters Comments on the Agent Du Jour XMRV at Zagreb Blood Conference

    June 23, 2010

    Pdfs of presentation slides from the IPFA/PEI Workshop on Surveillance and Screening of Blood Borne Pathogens (Zagreb, Croatia, May 26-27, 2010) are posted at the Workshop site.

    As famously noted June 22 by reporters for the Dutch publication ORTHO, the following is found on page 10 of NIH virologist Dr. Harvy Alters slide pack (Presentation 1, Session 4, Day 1):

    "Comments on the Agent Du Jour - XMRV

    The data in the Lombardi, et al. Science manuscript are extremely strong and likely true, despite the controversy.

    Not only have they detected gag and envelope XMRV sequences, but they have infected prostate cell lines and recovered gamma retrovirus particles and have transmitted XMRV to rhesus macaques by the IV route and demonstrated infectivity.

    Although blood transmission to humans has not been proved, it is probable.

    The association with CFS [Chronic Fatigue Syndrome] is very strong, but causality not proved.

    XMRV and related MLVs are in the donor supply with an early prevalence estimate of 3% - 7%.

    We (FDA & NIH) have independently confirmed the Lombardi group findings.

    Importantly, Dr. Alter is about as illustrious and respected as they come. Like most of the 'invisible illness' world, we Googled him & found a Wikipedia page (Harvey J. Alter - Wikipedia, the free encyclopedia) noting he is best known for his work leading to discovery of the hepatitis C virus.

    See also a presentation on XMRV & blood safety by Roger Y Dodd, PhD, director of the American Red Crosss Holland Lab in Rockville, Maryland. Dr. Dodds contribution titled Xenotropic Murine Leukemia virus (XMLV) Related virus and retrovirus diversity: Implications for blood safety is listed as Presentation 1, Session 3, Day 1. :He summarizes XMRV knowledge so far as follows:

    "Summary

    ERVs represent a complex and confusing field with many controversial observations (Human rumor viruses)

    XMRV is a recently identified gamma retrovirus infecting humans but apparently of mouse origin

    Associated with some, but not all cases of prostate cancer and CFS

    Variable expression (up to several percent) in normal controls

    Theoretically transmissible by transfusion

    Significance unclear, but obvious regulatory and public concerns
  7. leaves

    leaves Senior Member

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    Good idea!! (I can be bribed)
  8. V99

    V99 *****

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    If anyone wants me to do a leap for them the day this come out, it can be arranged
  9. Levi

    Levi Senior Member

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    Sickofcfs,

    Why waste the opportunity? If you guys REALLY want to invite cosmic level jinxing, then organize a PNAS release demonstration in front of CDC headquarters along the lines of THIS:

    http://www.flickr.com/photos/ficken/1813744832/sizes/m/in/photostream/
    [​IMG]


    And don't forget to invite the press . . .


  10. V99

    V99 *****

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    You could release a load of balloons with the words 'CDC was wrong about CFS" on them.
  11. VillageLife

    VillageLife Senior Member

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    :hug:
    I really hope this paper makes the newspapers!
  12. meadowlark

    meadowlark Senior Member

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    I have just breathed the deepest sigh of relief of my life. That means I have an awful lot to thank you for, Mindy. The anxiety about 'if' and 'when' has been like Chinese water torture. And I can live with not knowing the exact "when," as long as I know that it's near.

    Keep after the "forgetful" Dr. Monroe. It's superb that you refuse to go away.
  13. Eric Johnson from I&I

    Eric Johnson from I&I Senior Member

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    So, Early Edition is only on weekdays, and it looks like there is a particularly large amount of stuff on Mondays.

    Anyone know if Early Edition comes out at a regular time of day?
  14. V99

    V99 *****

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    Me too. If the result's haven't been tampered with, it will. Everywhere:hug:
  15. Eric Johnson from I&I

    Eric Johnson from I&I Senior Member

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    OK, I got it. PNAS says: "PNAS publishes new content online daily at 3 PM Eastern time." So yes, it appears that what we're looking for is a 3pm thing.
  16. pictureofhealth

    pictureofhealth XMRV - L'Agent du Jour

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    Thanks for staying on the case Mindy - its MUCH appreciated!

    George had the closest guess if I remember correctly (I think he suggested 3rd week in August). If he's right then Wow - how does he know these things?!!
  17. urbantravels

    urbantravels disjecta membra

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    I think George might have had the 24th as his guess, if I recall correctly.
  18. RustyJ

    RustyJ Contaminated Cell Line 'RustyJ'

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    It is likely that Alter will say many so-called CFS patients have XMRV and were misdiagnosed as CFS - they never did have CFS. Perhaps there will even be a few tut tuts and mentions of tragic injustices to people who are very ill. This seems to be the way the CDC new statement on CFS is shaping up. This will ensure that the CDC remains untarnished and actually exonerated. It will be a very pyrrhic victory for us. How does this then affect the pool? Is this what Levi was getting at?

    Every day that passes it become more apparent that if you carve out 80% of the existing CFS population you need a new name for those taken out. ME is too tarnished with CFS baggage. Did WPI foresee this day way back last year when they first coined the term XAND?

    In a few years time the general public (with gold fish-like mentality) will become aware of the disease XMRV, and forget that these people were once labelled as CFS. Sadly the remaining non XMRV people, being a much smaller group, will be forever tarnished with the baggage of the last few decades.

    And how does the CDC justify budgeting for just 20% under a dubious label of 'unrecognised psychological disorder', particularly when some of that 20% could have other RVs?

    PS. Are you sure George is a guy?
  19. Cloud

    Cloud Guest


    Well, my first thought is.....Who even needs a reason to celebrate anyhow. Lets party! LOl, but yea what Levi and Shrewsbury said.
  20. urbantravels

    urbantravels disjecta membra

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    I'm sorry, is George a she? I dunno what anybody is around here ... pictures of leaves, birds, dogs...I'm new:innocent1:

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