Whenever I feel fatigued my eyes become completely inflamed. I'm talking bloodshot with thick squiggly veins, dry, irritated/gritty and sensitive to just about everything (light and wind e.g.). Sometimes when I haven't slept enough, they also get this sunken look to them and consequently my dark circles become even more prominent. It mostly happens on days following a bad night's sleep. The whole following day I look like a complete mess and my eyes feel uncomfortable. Other days I wake up and feel fine. My eyes look bright and feel smooth, then towards late afternoon or early evening I often get hit with a wave of fatigue. I yawn every couple of minutes, my brain shuts off, anxiety, drowsiness and not to mention it looks like I have conjunctivitis/ocular rosacea. I get the same eye symptoms if I skip meals or go longer than, let's say 5 hours or more, without food/water. Eye drops that lubricate help marginally but I need to basically abuse them to have a noticeable lasting calming effect and they do nothing for the redness. The ones that "remove redness" help the most but I really don't like using them because of the rebound effect when I stop using them. Does anyone know what the mechanisms behind this could be? Seemingly every time I get fatigued my eyes get the worst of it..