Professor & patients' paper on the solvable biological challenge of ME/CFS: reader-friendly version
Simon McGrath provides a patient-friendly version of a peer-reviewed paper which highlights some of the most promising biomedical research on ME/CFS ...
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FAST TRACK APPROVAL FOR SFN DRUG ARA290.

Discussion in 'Other Health News and Research' started by Ema, Apr 20, 2015.

  1. Ema

    Ema Senior Member

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    Midwest USA
    Here's hoping this drug will benefit some of us in the ME/CFS/SEID/PENIS community as well. Looks promising!

     
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  2. valentinelynx

    valentinelynx Senior Member

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    Journal article with more information:
    ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response

    http://www.molecularpain.com/content/10/1/13

    Also, from PRNewswire (http://www.prnewswire.com/news-rele...ociated-small-fiber-neuropathy-280635872.html):

    "ARA 290 has also received orphan status with the FDA and by the European Regulatory Agency. Phase 3 trials are slated to begin 4Q 2015."
     
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  3. Marco

    Marco Grrrrrrr!

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    Near Cognac, France
    What I found interesting is that they had trialled this drug on sarcoidosis patients who reported decreased severity of symptoms of small fibre neuropathy compared to placebo as measured by the disease specific SFNSL instrument.

    But it wasn't the pain component of the scale that improved significantly but questions relating to autonomic function (including 'dry eyes', 'blurred vision' and 'dizzy when rising').

    Safety and Efficacy of ARA 290 in Sarcoidosis Patients with Symptoms of Small Fiber Neuropathy: A Randomized, Double-Blind Pilot Study

    http://static.smallworldlabs.com/molmedcommunity/content/pdfstore/12_332_Heij.pdf
     
    Bob and catly like this.

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